Boshier D P, Katz J M
J Reprod Fertil. 1976 Jul;47(2):245-9. doi: 10.1530/jrf.0.0470245.
Fructose-1,6-diphosphate (FDP) hydrolysis, which was measured in tissue extracts from mature rat endometrium, was maximal during late dioestrus and early pro-oestrus and reflected the variations in the plasma levels of ovarian steroids. Treatment of ovariectomized animals with oestradiol or medroxyprogesterone acetate increased FDP hydrolysis when compared with control animals, although oestradiol was the more effective. FDP hydrolysis was greater in extracts of endometrial tissue from uterine horns containing a silk IUD or of deciduomal tissue from pseudo-pregnant rats, in which the peak was on Day 9, than in extracts of endometrium from the control contralateral horn. These findings are interpreted as linking glycogen metabolism in normal endometrium, IUD-containing horns, and decidual tissue to the role of FDP in gluconeogenesis and the promotion of glycogen storage.
在成熟大鼠子宫内膜的组织提取物中所检测到的果糖-1,6-二磷酸（FDP）水解，在动情后期和动情前期早期达到最大值，反映了卵巢甾体激素血浆水平的变化。与对照动物相比，用雌二醇或醋酸甲羟孕酮处理去卵巢动物可增加FDP水解，尽管雌二醇的效果更佳。含有丝线宫内节育器的子宫角的子宫内膜组织提取物或假孕大鼠蜕膜组织提取物中的FDP水解，比对照对侧子宫角的子宫内膜提取物中的FDP水解更大，其中峰值出现在第9天。这些发现被解释为将正常子宫内膜、含宫内节育器的子宫角和蜕膜组织中的糖原代谢与FDP在糖异生和促进糖原储存中的作用联系起来。
