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[温度方案对温血动物和冷血动物蠕虫中脲酶的动力学和热力学功能的影响]

[Effect of the temperature regimen on the kinetic and thermodynamic functions of the enzyme urease in the helminths of warm-blooded and cold-blooded animals].

作者信息

Shishova-Kasatochkina O A, Koloskova T G, Sokhina L I

出版信息

Parazitologiia. 1976 Mar-Apr;10(3):232-7.

PMID:986602
Abstract

The determination of the constant of the urea fission rate and study of the temperature dependence (activation energy) of the urease activity on warm- and cold-blooded animals in Ascaris suum and Contracaecum aduncum were undertaken. It has been shown that the constant of the urea fission rate in C. aduncum is more than an order of magnitude higher than that in A. suum. At a temperature of 17 degrees the rate of this process in C. aduncum changes but little while in A. suum it practically ceases. On the contrary, at 47 degrees the urease ferment activity in A. suum increases considerably while in C. aduncum the process rate does not rise as compared to that at 37 degrees. The subsequent calculations of the energy activation have shown that a certain adaptation to definite conditions of ferments functioning can take place.

摘要

对猪蛔虫和钩状异尖线虫这两种温血动物和冷血动物体内尿素分解速率常数进行了测定,并研究了脲酶活性对温度的依赖性(活化能)。结果表明,钩状异尖线虫中尿素分解速率常数比猪蛔虫中的高一个数量级以上。在17摄氏度时,钩状异尖线虫中该过程的速率变化不大,而在猪蛔虫中实际上停止了。相反,在47摄氏度时,猪蛔虫中脲酶发酵活性显著增加,而钩状异尖线虫中的过程速率与37摄氏度时相比没有升高。随后对能量活化的计算表明,酶的功能可以对特定条件进行一定程度的适应。

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