珠蛋白信使核糖核酸含有一段与核内前体信使核糖核酸双链区域互补的序列。
Globin mRNA contains a sequence complementary to double-stranded region of nuclear pre-mRNA.
作者信息
Ryskov A P, Tokarskaya O V, Georgiev G P, Coutelle C, Thiele B
出版信息
Nucleic Acids Res. 1976 Jun;3(6):1487-98. doi: 10.1093/nar/3.6.1487.
Abstract
Melted ds RNA isolated from rabbit bone marrow pre-mRNA was hybridized with excess of globin mRNA which was prepared from rabbit reticulocytes. 7-9% of ds sequences became RNAase-stable and about 30% of the sequences could be bound to poly(U)-Sepharose through poly (A) of mRNA. The size of RNAase-stable hybrid is about 30 nucleotides, that is one fourth of the length of one strand of the ds RNA.
摘要
从兔骨髓前体mRNA中分离出的融化双链RNA与过量的兔网织红细胞制备的珠蛋白mRNA杂交。7-9%的双链序列变得对RNA酶稳定，约30%的序列可通过mRNA的聚腺苷酸与聚尿苷琼脂糖结合。对RNA酶稳定的杂交体大小约为30个核苷酸，即双链RNA一条链长度的四分之一。
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Globin mRNA contains a sequence complementary to double-stranded region of nuclear pre-mRNA.珠蛋白信使核糖核酸含有一段与核内前体信使核糖核酸双链区域互补的序列。
Nucleic Acids Res. 1976 Jun;3(6):1487-98. doi: 10.1093/nar/3.6.1487.
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Some unusual properties of globin-mRNA isolated from rabbit reticulocytes.
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The putative 15 S precursor of globin mRNA contains a poly (A) sequence.假定的珠蛋白信使核糖核酸15S前体含有一个多聚腺苷酸序列。
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Organization of sequences of avian globin mRNA.鸟类珠蛋白信使核糖核酸序列的组织
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[Globin-coding sequences in the nuclear 28S pre-mRNA and in the cytoplasmic RNA of pigeon erythroid cells].[鸽类红细胞细胞核28S前体mRNA和细胞质RNA中的珠蛋白编码序列]
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Direct demonstration of a complementarity between mRNA and double-stranded sequences of pre-mRNA.直接证明信使核糖核酸（mRNA）与信使核糖核酸前体（pre-mRNA）双链序列之间的互补性。
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Shortening of the poly(A) tail at the 3'-end of mRNA requires its translation.mRNA 3' 端多聚腺苷酸尾巴的缩短需要其进行翻译。
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引用本文的文献
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The nucleotide sequence of the ubiquitous repetitive DNA sequence B1 complementary to the most abundant class of mouse fold-back RNA.与最丰富的一类小鼠回折RNA互补的普遍存在的重复DNA序列B1的核苷酸序列。
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Sequences hybridizing to mRNA, oligo(dT) and dsRNA from pre-mRNA are contiguous in the cloned mouse DNA fragments.与mRNA、寡聚（dT）以及来自前体mRNA的双链RNA杂交的序列，在克隆的小鼠DNA片段中是连续的。
Nucleic Acids Res. 1980 Feb 11;8(3):425-40. doi: 10.1093/nar/8.3.425.
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Methylated cap formation by enzymes bound to nuclear informofer particles.
Mol Biol Rep. 1978 Jun 16;4(2):93-6. doi: 10.1007/BF00775967.
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Secondary structure of heterogeneous nuclear RNA: two classes of double-stranded RNA in native ribonucleoprotein.不均一核RNA的二级结构：天然核糖核蛋白中的两类双链RNA
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Presence of a putative 15S precursor to beta-globin mRNA but not to alpha-globin mRNA in Friend cells.弗瑞德（Friend）细胞中存在β-珠蛋白mRNA的假定15S前体，但不存在α-珠蛋白mRNA的假定15S前体。
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Long double-stranded sequences (dsRNA-B) of nuclear pre-mRNA consist of a few highly abundant classes of sequences: evidence from DNA cloning experiments.核内前体信使核糖核酸的长双链序列（dsRNA-B）由几类高度丰富的序列组成：来自DNA克隆实验的证据。
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Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen.通过与补骨脂素衍生物氨甲基三氧杂补骨脂素交联，在活的HeLa细胞中探测到的异质核RNA双链区域。
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本文引用的文献
1
Hemoglobin messenger ribonucleic acid. Synthesis of 9S and ribosomal ribonucleic acid during erythroid cell development.血红蛋白信使核糖核酸。红细胞生成过程中9S和核糖体核糖核酸的合成。
Biochemistry. 1969 Jul;8(7):3000-5. doi: 10.1021/bi00835a048.
2
The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis.用聚丙烯酰胺凝胶电泳法分离高分子量核糖核酸
Biochem J. 1967 Jan;102(1):251-7. doi: 10.1042/bj1020251.
3
On the structure of transcriptional unit in mammalian cells.关于哺乳动物细胞中转录单位的结构。
Biochim Biophys Acta. 1972 Jan 31;259(2):259-83. doi: 10.1016/0005-2787(72)90066-4.
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Double-helical regions in nuclear precursor of mRNA (pre-mRNA).信使核糖核酸前体（前体mRNA）中的双螺旋区域。
Biochim Biophys Acta. 1973 Jun 8;312(1):152-64. doi: 10.1016/0005-2787(73)90060-9.
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Biochemistry. 1974 Dec 17;13(26):5373-8. doi: 10.1021/bi00723a019.
6
Cleavage by RNase 3 converts T3 and T7 early precursor RNA into translatable message.核糖核酸酶3的切割作用将T3和T7早期前体RNA转化为可翻译的信使RNA。
Proc Natl Acad Sci U S A. 1974 Mar;71(3):840-4. doi: 10.1073/pnas.71.3.840.
7
Synthesis of a large precursor to ribosomal RNA in a mutant of Escherichia coli.大肠杆菌突变体中核糖体RNA大前体的合成。
Proc Natl Acad Sci U S A. 1973 Dec;70(12):3361-5. doi: 10.1073/pnas.70.12.3361.
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T7 early RNAs and Escherichia coli ribosomal RNAs are cut from large precursor RNAs in vivo by ribonuclease 3.T7早期RNA和大肠杆菌核糖体RNA在体内由核糖核酸酶3从大的前体RNA中切割而来。
Proc Natl Acad Sci U S A. 1973 Dec;70(12):3296-3300. doi: 10.1073/pnas.70.12.3296.
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