O'Connor M K, Kanal K M, Gebhard M W, Rossman P J
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Nucl Med. 1998 Dec;39(12):2027-34.
The aim of this study was to evaluate the accuracy of four different motion correction techniques in SPECT imaging of the heart.
We evaluated three automated techniques: the cross-correlation (CC) method, diverging squares (DS) method and two-dimensional fit method and one manual shift technique (MS) using a cardiac phantom. The phantom was filled with organ concentrations of 99mTc closely matching those seen in patient studies. The phantom was placed on a small sliding platform connected to a computer-controlled stepping motor. Linear, random, sinusoidal and bounce motions of magnitude up to 2 cm in the axial direction were simulated. Both single- and dual-detector 90 degrees acquisitions were acquired using a dual 90 degrees detector system. Data were acquired over 180 degrees with 30 or 15 frames/detector (single-/dual-head) at 30 sec/frame in a 64x64 matrix.
The simulated single-detector system, CC method, failed to accurately correct for any of the simulated motions. The DS technique overestimated the magnitude of phantom motion, particularly for images acquired between 45 degrees left anterior oblique and 45 degrees left posterior oblique. The two-dimensional and MS techniques accurately corrected for motion. The simulated dual 90 degrees detector system, CC method, only partially tracked random or bounce cardiac motion and failed to detect sinusoidal motion. The DS technique overestimated motion in the latter half of the study. Both the two-dimensional and MS techniques provided superior tracking, although no technique was able to accurately track the rapid changes in cardiac location simulated in the random motion study. Average absolute differences between true and calculated position of the heart on single- and dual 90 degrees -detectors were 1.7 mm and 1.5 mm for the two-dimensional and MS techniques, respectively. The corresponding values for the DS and CC techniques were 5.7 and 8.9 mm, respectively.
Of the four techniques evaluated, manual correction by an experienced technologist proved to be the most accurate, although results were not significantly different from those observed with the two-dimensional method. Both techniques accurately determined cardiac location and permitted artifact-free reconstruction of the simulated cardiac studies.
本研究的目的是评估四种不同运动校正技术在心脏SPECT成像中的准确性。
我们使用心脏模型评估了三种自动技术:互相关(CC)法、发散方块(DS)法和二维拟合方法,以及一种手动移位技术(MS)。模型中填充的99mTc器官浓度与患者研究中观察到的浓度紧密匹配。模型放置在连接到计算机控制步进电机的小型滑动平台上。模拟了轴向幅度高达2厘米的线性、随机、正弦和跳动运动。使用双90度探测器系统进行单探测器和双探测器90度采集。数据在180度范围内采集,单头/双头探测器每帧30秒,30或15帧/探测器(单头/双头),矩阵为64x64。
模拟的单探测器系统CC法未能准确校正任何模拟运动。DS技术高估了模型运动的幅度,特别是对于在左前斜45度和左后斜45度之间采集的图像。二维和MS技术准确校正了运动。模拟的双90度探测器系统CC法仅部分跟踪了随机或跳动的心脏运动,未能检测到正弦运动。DS技术在研究后半段高估了运动。二维和MS技术都提供了更好的跟踪效果,尽管没有一种技术能够准确跟踪随机运动研究中模拟的心脏位置的快速变化。二维和MS技术在单90度和双90度探测器上心脏真实位置与计算位置的平均绝对差值分别为1.7毫米和1.5毫米。DS和CC技术的相应值分别为5.7毫米和8.9毫米。
在所评估的四种技术中,经验丰富的技术人员进行的手动校正被证明是最准确的,尽管结果与二维方法观察到的结果没有显著差异。两种技术都准确确定了心脏位置,并允许对模拟心脏研究进行无伪影重建。