Cruz A C, Buhi W C, Birk S A, Spellacy W N
Am J Obstet Gynecol. 1976 Sep 1;126(1):78-82. doi: 10.1016/0002-9378(76)90468-3.
A detailed study was made of 150 women delivered of their infants within 72 hours of an amniocentesis where the lecithin/sphingomyelin (L/S) ratio was 2.0 or greater. There were nine neonates with respiratory distress (6.0 per cent). There were two neonatal deaths, both due to severe congenital heart disease. A mature amniotic fluid L/S ratio predicts a newborn infant who will not have respiratory distress syndrome (RDS) in most pregnancies. There is a significantly increased risk of RDS in neonates with a mature L/S ratio if the mother has insulin-dependent diabetes or if there is a resulting low Apgar score. The method of delivery (cesarean section or vaginal) does not affect the frequency of RDS where the L/S ratio is 2.0 or more.
对150名在羊膜穿刺术后72小时内分娩的妇女进行了详细研究，这些妇女的卵磷脂/鞘磷脂（L/S）比值为2.0或更高。有9名新生儿出现呼吸窘迫（6.0%）。有2例新生儿死亡，均死于严重先天性心脏病。在大多数妊娠中，成熟的羊水L/S比值预示新生儿不会患呼吸窘迫综合征（RDS）。如果母亲患有胰岛素依赖型糖尿病或导致阿氏评分低，则L/S比值成熟的新生儿患RDS的风险会显著增加。分娩方式（剖宫产或阴道分娩）不影响L/S比值为2.0或更高时RDS的发生率。
