来自汤氏红厚壳（Crossopetalum tonduzii）的新型倍半萜类化合物。

New sesquiterpenes from Crossopetalum tonduzii.

作者信息

Tincusi B M, Jiménez I A, Ravelo A G, Missico R

机构信息

Instituto Universitario de Bio-Orgánica "Antonio González", Universidad de La Laguna, Avenida Astrofísico Francisco Sánchez 2, La Laguna, 38206 Tenerife, Canary Islands, Spain.

出版信息

J Nat Prod. 1998 Dec;61(12):1520-3. doi: 10.1021/np980229g.

DOI:10.1021/np980229g

PMID:9868155

Abstract

Five new sesquiterpenes (1-5) with a dihydro-beta-agarofuran skeleton were isolated from Crossopetalum tonduzii. Their structures were elucidated by means of 1H and 13C NMR spectroscopic studies, including homonuclear and heteronuclear correlation experiments (COSY, ROESY, HMQC, and HMBC). The absolute configurations of 1 and 2 were determined by CD studies and chemical correlation. Compounds 1-3 were assayed against Spodoptera littoralis in an election test and showed low insect-antifeedant activity.

摘要

从顿氏十字花瓣木（Crossopetalum tonduzii）中分离出了5个具有二氢-β-agarofuran骨架的新倍半萜（1-5）。通过1H和13C NMR光谱研究，包括同核和异核相关实验（COSY、ROESY、HMQC和HMBC）阐明了它们的结构。通过圆二色光谱（CD）研究和化学关联确定了1和2的绝对构型。在一项筛选试验中对化合物1-3针对斜纹夜蛾进行了测定，结果显示其具有较低的昆虫拒食活性。