Kesäniemi Y A
Department of Internal Medicine and Biocentre Oulu, University of Oulu, Finland.
Curr Opin Lipidol. 1998 Dec;9(6):571-4. doi: 10.1097/00041433-199812000-00009.
Triglyceride metabolism is complex and still poorly understood. Hypertriglyceridemia seems to enhance the risk for the development of coronary heart disease, but it cannot be regarded as a counterpart of hypercholesterolemia as a risk factor. The relevance of reduction of triglycerides in the prevention of coronary heart disease is still unclear. This is related to a number of problems, such as the lack of adequate clinical trials, heterogeneity in the abnormalities of triglyceride metabolism and unknown atherogenic threshold levels for serum triglycerides.
甘油三酯代谢复杂，目前仍了解不足。高甘油三酯血症似乎会增加冠心病发生的风险，但它不能被视为与高胆固醇血症具有同等地位的风险因素。降低甘油三酯在预防冠心病方面的相关性仍不明确。这与一些问题有关，如缺乏充分的临床试验、甘油三酯代谢异常的异质性以及血清甘油三酯致动脉粥样硬化阈值水平不明等。
