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暴露于重离子的平行板电离室中的初始复合。

Initial recombination in a parallel-plate ionization chamber exposed to heavy ions.

作者信息

Kanai T, Sudo M, Matsufuji N, Futami Y

机构信息

Therapeutic Beam Assessment Office, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan.

出版信息

Phys Med Biol. 1998 Dec;43(12):3549-58. doi: 10.1088/0031-9155/43/12/012.

Abstract

For exact determination of absorbed dose in heavy-ion irradiation fields which are used in radiation therapy and biological experiments, ionization chambers have been characterized with defined heavy-ion beams and correction factors. The LET (linear energy transfer) dependence of columnar recombination in a parallel-plate ionization chamber has been examined. Using 135 MeV/u carbon and neon beams, the ion collection efficiency was measured for several gases (air, carbon dioxide, argon and tissue-equivalent gas). 95 MeV/u argon beams and 90 MeV/u iron beams were also used for measurements of columnar recombination in air. As expected by Jaffe theory, the inverse of the ratio of the ionization charge to the saturated ionization charge had a linear relationship with the inverse of the electric field strength in the region below 0.002 V(-1) cm. The gradient of the line increases as the LET of the heavy ions increases. A strong LET dependence of the gradient was observed in air and carbon dioxide. The LET dependence was not observed in tissue-equivalent gas, nitrogen or argon. The exact depth-dose distribution of the heavy-ion beam was obtained by this correction of the initial recombination effect for the collected ionization charge. The columnar recombination in air was analysed using Jaffe theory; the obtained parameter b (a track radius) should be in the range between 0.001 cm and 0.005 cm, whereas the value obtained by Jaffe is 0.00179 cm. The value of the parameter b should increase as the LET of the heavy-ion beam increases in order to reproduce the experimental values of the initial recombination.

摘要

为了精确测定用于放射治疗和生物学实验的重离子辐照场中的吸收剂量,已使用定义的重离子束和校正因子对电离室进行了表征。研究了平行板电离室中柱状复合的传能线密度(LET)依赖性。使用135 MeV/u的碳离子束和氖离子束,测量了几种气体(空气、二氧化碳、氩气和组织等效气体)的离子收集效率。还使用95 MeV/u的氩离子束和90 MeV/u的铁离子束测量了空气中的柱状复合。正如贾菲理论所预期的那样,在低于0.002 V⁻¹ cm的区域中,电离电荷与饱和电离电荷之比的倒数与电场强度的倒数呈线性关系。随着重离子LET的增加,直线的斜率增大。在空气和二氧化碳中观察到斜率对LET有很强的依赖性。在组织等效气体、氮气或氩气中未观察到LET依赖性。通过对收集到的电离电荷的初始复合效应进行这种校正,获得了重离子束精确的深度剂量分布。使用贾菲理论分析了空气中的柱状复合;得到的参数b(径迹半径)应在0.001 cm至0.005 cm之间,而贾菲得到的值为0.00179 cm。为了重现初始复合的实验值,参数b的值应随着重离子束LET的增加而增大。

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