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Novel D-ring analogues of podophyllotoxin as potent anti-cancer agents.

作者信息

Subrahmanyam D, Renuka B, Rao C V, Sagar P S, Deevi D S, Babu J M, Vyas K

机构信息

Natural Products Division, Dr. Reddy's Research Foundation, Miyapur, Hyderabad, India.

出版信息

Bioorg Med Chem Lett. 1998 Jun 2;8(11):1391-6. doi: 10.1016/s0960-894x(98)00232-7.

DOI:10.1016/s0960-894x(98)00232-7
PMID:9871772
Abstract

Several D-ring modified analogues of podophyllotoxin were prepared viz semi-synthesis starting from naturally occurring podophyllotoxin and determined their in vitro anti-cancer activity. Most of the analogues have shown good activity towards human cancer cell lines.

摘要

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