Subrahmanyam D, Renuka B, Rao C V, Sagar P S, Deevi D S, Babu J M, Vyas K
Natural Products Division, Dr. Reddy's Research Foundation, Miyapur, Hyderabad, India.
Bioorg Med Chem Lett. 1998 Jun 2;8(11):1391-6. doi: 10.1016/s0960-894x(98)00232-7.
Several D-ring modified analogues of podophyllotoxin were prepared viz semi-synthesis starting from naturally occurring podophyllotoxin and determined their in vitro anti-cancer activity. Most of the analogues have shown good activity towards human cancer cell lines.