Feldman-Naim S, Lowe C H, Myers F S, Turner E H, Weinstock L M, Leibenluft E
Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, Maryland 20892-1255, USA.
Depress Anxiety. 1998;8(4):166-8.
We validated the Hypomania Interview Guide-Seasonal Affective Disorder version (HIGH-SAD) in patients with rapid cycling bipolar disorder (RCBD). Fourteen outpatients were rated on six separate occasions (total = 84 visits). On each visit the patients were rated with the HIGH-SAD and the Young Mania Rating Scale (YMRS) in a counterbalanced order. Clinical assessment was completed at the end of the visit by the treating psychiatrist. Patients were assessed as hypomanic/manic on 22 of the visits. Pearson correlation coefficient between the YMRS total scores and the HIGH-SAD total scores for those 22 visits in which patients were hypomanic/manic was r = 0.629 (P < 0.05) and for all visits was r = 0.769 (P < 0.0001). Analysis with only one rating per patient yielded a Pearson correlation coefficient of r = 0.792 (P < 0.0004). We found that the HIGH-SAD was a valid scale for the measurement of hypomania in patients with RCBD. However, the scale does not differentiate hypomania from mania in this group of patients.
我们在快速循环型双相情感障碍（RCBD）患者中验证了轻躁狂访谈指南-季节性情感障碍版（HIGH-SAD）。对14名门诊患者进行了6次独立评估（共84次就诊）。每次就诊时，以平衡顺序使用HIGH-SAD和青年躁狂评定量表（YMRS）对患者进行评分。就诊结束时由主治精神科医生完成临床评估。在22次就诊中，患者被评定为轻躁狂/躁狂。在患者为轻躁狂/躁狂的这22次就诊中，YMRS总分与HIGH-SAD总分的Pearson相关系数为r = 0.629（P < 0.05），在所有就诊中该系数为r = 0.769（P < 0.0001）。对每位患者仅进行一次评分的分析得出Pearson相关系数为r = 0.792（P < 0.0004）。我们发现，HIGH-SAD是测量RCBD患者轻躁狂的有效量表。然而，该量表在这组患者中无法区分轻躁狂和躁狂。
