Boffetta P, Sali D, Kolstad H, Coggon D, Olsen J, Andersen A, Spence A, Pesatori A C, Lynge E, Frentzel-Beyme R, Chang-Claude J, Lundberg I, Biocca M, Gennaro V, Teppo L, Partanen T, Welp E, Saracci R, Kogevinas M
International Agency for Research on Cancer, Lyon, France.
J Occup Environ Med. 1998 Dec;40(12):1120-6. doi: 10.1097/00043764-199812000-00012.
The purpose of this study was to compare the pattern of mortality of blue-collar workers employed less and more than 1 year in the man-made vitreous fiber (MMVF) and the reinforced plastic industries, the latter group being exposed to styrene. We conducted an analysis among 21,784 workers with less than 1 year of employment (short-term workers) and 19,117 workers with 1 or more years of employment (long-term workers) employed in eight European countries. We conducted analyses based on external as well as internal comparisons. In both cohorts, the standardized mortality ratio for all causes among short-term workers was approximately 40% higher, compared with that for longer-term workers. In internal comparisons, the difference was reduced to 9% in the MMVF cohort and 11% in the styrene cohort. Workers with less than 1 month of employment displayed an increased mortality in both cohorts and in most countries. The increased mortality among short-term workers was not concentrated shortly after they quit employment. In both cohorts, short-term workers had a higher mortality from external causes, while little difference was seen in mortality from ischemic heart disease and malignant neoplasms. Although extra-occupational factors may contribute to increase the mortality of short-term workers and, in particular, of those employed for less than 1 month, the difference observed in analyses adjusted for characteristics of employment suggested a relatively small difference in mortality from most causes.
本研究的目的是比较在人造玻璃纤维(MMVF)和增强塑料行业中工作年限少于1年和多于1年的蓝领工人的死亡率模式,后者接触苯乙烯。我们对欧洲八个国家的21784名工作年限少于1年的工人(短期工人)和19117名工作年限为1年或更长时间的工人(长期工人)进行了分析。我们基于外部比较和内部比较进行了分析。在两个队列中,短期工人所有原因的标准化死亡比与长期工人相比大约高40%。在内部比较中,MMVF队列中的差异降至9%,苯乙烯队列中的差异降至11%。工作年限少于1个月的工人在两个队列以及大多数国家中死亡率都有所增加。短期工人死亡率的增加并非集中在他们离职后不久。在两个队列中,短期工人因外部原因导致的死亡率更高,而在缺血性心脏病和恶性肿瘤导致的死亡率方面差异不大。尽管职业外因素可能导致短期工人尤其是工作年限少于1个月的工人死亡率增加,但在根据就业特征进行调整的分析中观察到的差异表明,大多数原因导致的死亡率差异相对较小。