Seidel W, Pischetsrieder M
Institut für Pharmazie und Lebensmittelchemie der Universität München, Germany.
Bioorg Med Chem Lett. 1998 Aug 4;8(15):2017-22. doi: 10.1016/s0960-894x(98)00343-6.
Incubation of glucose with guanosine under oxidative conditions at 37 degrees C or 70 degrees C leads to the formation of a main product, which can be detected by HPLC/DAD. The compound was isolated and identified as N2-carboxymethyl-guanosine (CMG). To confirm the structure, CMG was also synthesized from glyoxal and guanosine.
葡萄糖与鸟苷在37℃或70℃氧化条件下孵育会生成一种主要产物，该产物可通过高效液相色谱/二极管阵列检测器（HPLC/DAD）检测到。该化合物被分离并鉴定为N2-羧甲基鸟苷（CMG）。为确认其结构，CMG也由乙二醛和鸟苷合成得到。
