Csata S, Kulcsár G, Verebélyi A
Department of Urology, St. István Hospital, Budapest, Hungary.
Acta Microbiol Immunol Hung. 1998;45(3-4):291-5.
The possible connection of viruses with tumours was investigated by serologic examinations. Concerning the presence of antibodies against adenoviruses, especially those against the early non-virion antigens of oncogenic adenovirus type 12, approximately 4000 tests were made with sera of 446 urogenital patients with and without tumours and 70 ones with internal diseases. It was found by complement fixation tests that antibodies against nonvirion antigens of adenoviruses were present in 53% of urogenital patients suffering from malignant tumours and prostatic hypertrophy, in 18% of non-tumourous urological patients and in 4% of patients with internal diseases, respectively. The results suggest that adenoviruses may play a role in tumourous diseases of the urogenital organs.
通过血清学检查对病毒与肿瘤之间可能存在的联系进行了研究。关于抗腺病毒抗体的存在情况，特别是针对致癌性12型腺病毒早期非病毒体抗原的抗体，对446名患有和未患有肿瘤的泌尿生殖系统疾病患者以及70名患有内科疾病的患者的血清进行了约4000次检测。通过补体结合试验发现，在患有恶性肿瘤和前列腺肥大的泌尿生殖系统疾病患者中，53%存在抗腺病毒非病毒体抗原的抗体；在非肿瘤性泌尿系统疾病患者中，18%存在该抗体；在内科疾病患者中，4%存在该抗体。结果表明，腺病毒可能在泌尿生殖器官的肿瘤性疾病中起作用。
