St-Jean P, Sadikot A F, Collins L, Clonda D, Kasrai R, Evans A C, Peters T M
McConnell Brain Imaging Centre and the Department of Neurology and Neurosurgery, Montréal Neurological Institute and Hospital, McGill University, PQ, Canada.
IEEE Trans Med Imaging. 1998 Oct;17(5):672-80. doi: 10.1109/42.736017.
Many critical functionally distinct subcortical structures are not distinguishable on anatomical magnetic resonance imaging (MRI) scans. In order to provide the neurosurgeon with this missing information, a deformable volumetric atlas of the basal ganglia and thalamus has been created from the Schaltenbrand and Wahren atlas of cryogenic slices. The volumetric atlas can be automatically deformed to an individual patient's MRI. To facilitate the clinical use of the atlas, a visualization platform has been developed for preoperative and intraoperative use which permits manipulation of the merged atlas and MRI data sets in two- and three-dimensional views. The platform includes graphical tools which allow the visualization of projections of a leukotome and other surgical tools with respect to the atlas data, as well as preregistered images from any other imaging modality. In addition, a graphical interface has been designed to create custom virtual lesions using computer models of neurosurgical tools for intraoperative planning. To date this system has been employed as an adjunct to over 30 functional neurosurgical cases including surgery for movement disorders.
许多关键的、功能不同的皮质下结构在解剖磁共振成像（MRI）扫描中无法区分。为了向神经外科医生提供这些缺失的信息，已根据Schaltenbrand和Wahren的低温切片图谱创建了基底神经节和丘脑的可变形体积图谱。该体积图谱可以自动变形为个体患者的MRI图像。为便于该图谱在临床上的使用，已开发了一个可视化平台，用于术前和术中，该平台允许在二维和三维视图中操作合并后的图谱和MRI数据集。该平台包括图形工具，可实现白质切开刀和其他手术工具相对于图谱数据的投影可视化，以及来自任何其他成像模态的预配准图像。此外，还设计了一个图形界面，用于使用神经外科工具的计算机模型创建定制虚拟病变，以进行术中规划。迄今为止，该系统已作为辅助工具应用于30多例功能神经外科手术病例，包括运动障碍手术。
