儿童血铅水平升高与促红细胞生成素浓度降低有关。

Elevated blood lead levels in children are associated with lower erythropoietin concentrations.

作者信息

Liebelt E L, Schonfeld D J, Gallagher P

机构信息

Department of Pediatrics and The Children's Clinical Research Center, Yale University School of Medicine; New Haven, Connecticut, USA.

出版信息

J Pediatr. 1999 Jan;134(1):107-9. doi: 10.1016/s0022-3476(99)70381-1.

DOI:10.1016/s0022-3476(99)70381-1

PMID:9880459

Abstract

Eighty-six children (mean age, 34 months) were studied to determine whether elevated blood lead levels in children are associated with lower erythropoietin concentrations. The median erythropoietin concentration was 5.9 mIU/mL (range, 2.3 to 11.5 mIU/mL), and the median blood lead level was 0.87 micromol/L (18 microg/dL; range, 2 to 84 microg/dL). Blood lead concentration was inversely and independently related to erythropoietin concentration.

摘要

对86名儿童（平均年龄34个月）进行了研究，以确定儿童血铅水平升高是否与促红细胞生成素浓度降低有关。促红细胞生成素浓度中位数为5.9 mIU/mL（范围为2.3至11.5 mIU/mL），血铅水平中位数为0.87微摩尔/升（18微克/分升；范围为2至84微克/分升）。血铅浓度与促红细胞生成素浓度呈负相关且独立相关。