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胆总管十二指肠连接部胆汁排泄机制的实验研究(作者译)

[An experimental study on the mechanism of bile excretion of the choledochoduodenal junction (author's transl)].

出版信息

Nihon Heikatsukin Gakkai Zasshi. 1976 Sep;12(3):139-55.

PMID:988403
Abstract

The present study was undertaken to elucidate the mechanism of bile excretion of the choledochoduodenal junction (ch-d junction) in rabbits, especially regarding it's structural and physiological independence from the duodenum. For this purpose muscular anatomy of the ch-d junction and relationship between the electromygoraphic spike potential of the juncture and the intracholedochal pressure were investigated. 1. There were demonstrated proper circular muscle and proper oblique muscle in the ch-d junction, which appeared independent from the duodenal muscle. There existed A MUSCULAR SPHINCTER at the terminus of the common bile duct, but it's muscle fibers did not appear continuous with the duodenal muscle fibers. 2. The rhythmical changing curve of the intracholedochal pressure was parallel with appearance of the spike potential but had absolutely no correlation with the duodenal one. 3. The attitudes of the ch-d junction and the duodenum to the neural control were compared. The spike generation by Neostigmin METHYLSULFATE WAS EQUALLY OBSERVED IN THE CH-D JUNCTION and the duodenum and the spike inhibition by Hyoscin-N-butylbromide was also equally observed in both of them, SUGGESTING THEIR innervation was probably common.

摘要

本研究旨在阐明家兔胆总管十二指肠连接处(ch-d连接处)胆汁排泄的机制,尤其是其在结构和生理上与十二指肠的独立性。为此,研究了ch-d连接处的肌肉解剖结构以及该连接处的肌电图棘波电位与胆总管内压之间的关系。1. 在ch-d连接处发现了固有环行肌和固有斜肌,它们似乎独立于十二指肠肌。在胆总管末端存在一个肌肉括约肌,但其肌纤维与十二指肠肌纤维不连续。2. 胆总管内压的节律性变化曲线与棘波电位的出现平行,但与十二指肠的曲线绝对没有相关性。3. 比较了ch-d连接处和十二指肠对神经控制的反应。在ch-d连接处和十二指肠均同样观察到硫酸新斯的明引起的棘波产生,并且在两者中也同样观察到丁溴东莨菪碱引起的棘波抑制,这表明它们的神经支配可能是共同的。

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