溶血素作为鸟分枝杆菌复合群分离株引起全身感染的一种毒力因子。
Hemolysin as a virulence factor for systemic infection with isolates of Mycobacterium avium complex.
作者信息
Maslow J N, Dawson D, Carlin E A, Holland S M
机构信息
Infectious Diseases Section, Medical Service, VA Medical Center, and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02130, USA.
出版信息
J Clin Microbiol. 1999 Feb;37(2):445-6. doi: 10.1128/JCM.37.2.445-446.1999.
Abstract
Isolates of the Mycobacterium avium complex were examined for hemolysin expression. Only invasive isolates of M. avium were observed to be hemolytic (P < 0.001), with activity the greatest for isolates of serovars 4 and 8. Thus, M. avium hemolysin appears to represent a virulence factor necessary for invasive disease.
摘要
对鸟分枝杆菌复合体的分离株进行溶血素表达检测。仅观察到鸟分枝杆菌的侵袭性分离株具有溶血活性（P < 0.001），其中血清型4和8的分离株活性最强。因此，鸟分枝杆菌溶血素似乎是侵袭性疾病所必需的一种毒力因子。
相似文献
1
Hemolysin as a virulence factor for systemic infection with isolates of Mycobacterium avium complex.溶血素作为鸟分枝杆菌复合群分离株引起全身感染的一种毒力因子。
J Clin Microbiol. 1999 Feb;37(2):445-6. doi: 10.1128/JCM.37.2.445-446.1999.
2
Most human isolates of Mycobacterium avium Mav-A and Mav-B are strong producers of hemolysin, a putative virulence factor.鸟分枝杆菌Mav - A和Mav - B的大多数人类分离株都是溶血素的强生产者，溶血素是一种假定的毒力因子。
J Clin Microbiol. 2003 Dec;41(12):5738-40. doi: 10.1128/JCM.41.12.5738-5740.2003.
3
Comparison of virulence of Mycobacterium avium complex (MAC) strains isolated from AIDS and non-AIDS patients.从艾滋病患者和非艾滋病患者中分离出的鸟分枝杆菌复合群（MAC）菌株的毒力比较。
Microb Pathog. 1994 Feb;16(2):121-30. doi: 10.1006/mpat.1994.1013.
4
Immunomodulatory events in Mycobacterium avium infections.鸟分枝杆菌感染中的免疫调节事件。
Res Microbiol. 1994 Mar-Apr;145(3):225-9. doi: 10.1016/0923-2508(94)90022-1.
5
Mycobacterium avium: pathogenicity in HIV1 infection.鸟分枝杆菌：在HIV-1感染中的致病性
Res Microbiol. 1994 Mar-Apr;145(3):230-6. doi: 10.1016/0923-2508(94)90023-x.
6
Haemolysin from Mycobacterium avium complex isolates from AIDS patients.从艾滋病患者分离出的鸟分枝杆菌复合群中的溶血素。
J Med Microbiol. 1998 Apr;47(4):365-7. doi: 10.1099/00222615-47-4-365.
7
Species identification of Mycobacterium avium complex isolates by a variety of molecular techniques.通过多种分子技术对鸟分枝杆菌复合群分离株进行菌种鉴定。
J Clin Microbiol. 2000 Feb;38(2):508-12. doi: 10.1128/JCM.38.2.508-512.2000.
8
Differential virulence of Mycobacterium avium strains isolated from HIV-infected patients with disseminated M. avium complex disease.从播散性鸟分枝杆菌复合群病的HIV感染患者中分离出的鸟分枝杆菌菌株的毒力差异。
J Infect Dis. 2004 Oct 1;190(7):1347-54. doi: 10.1086/424488. Epub 2004 Aug 31.
9
Haemolytic activity of Mycobacterium spp.分枝杆菌属的溶血活性
Acta Microbiol Pol. 1997;46(4):377-85.
10
Submandibular gland infection by Mycobacterium avium-intracellulare in an AIDS patient.一名艾滋病患者的颌下腺鸟分枝杆菌-胞内分枝杆菌感染。
Eur J Clin Microbiol Infect Dis. 1998 Jul;17(7):529-35. doi: 10.1007/BF01691141.
引用本文的文献
1
Discovery of stable and variable differences in the Mycobacterium avium subsp. paratuberculosis type I, II, and III genomes by pan-genome microarray analysis.通过泛基因组微阵列分析发现鸟分枝杆菌副结核亚种I型、II型和III型基因组中的稳定和可变差异。
Appl Environ Microbiol. 2009 Feb;75(3):676-86. doi: 10.1128/AEM.01683-08. Epub 2008 Dec 1.
2
Distribution of hsp65 PCR-restriction enzyme analysis patterns among Mycobacterium avium complex isolates in Thailand.泰国鸟分枝杆菌复合群分离株中hsp65 PCR-限制性内切酶分析模式的分布情况
J Clin Microbiol. 2006 Oct;44(10):3819-21. doi: 10.1128/JCM.02495-05. Epub 2006 Aug 23.
3
Utilization of a ts-sacB selection system for the generation of a Mycobacterium avium serovar-8 specific glycopeptidolipid allelic exchange mutant.利用ts-sacB选择系统生成鸟分枝杆菌血清型8特异性糖肽脂等位基因交换突变体。
Ann Clin Microbiol Antimicrob. 2004 Sep 30;3:18. doi: 10.1186/1476-0711-3-18.
4
Most human isolates of Mycobacterium avium Mav-A and Mav-B are strong producers of hemolysin, a putative virulence factor.鸟分枝杆菌Mav - A和Mav - B的大多数人类分离株都是溶血素的强生产者，溶血素是一种假定的毒力因子。
J Clin Microbiol. 2003 Dec;41(12):5738-40. doi: 10.1128/JCM.41.12.5738-5740.2003.
5
Species identification of Mycobacterium avium complex isolates by a variety of molecular techniques.通过多种分子技术对鸟分枝杆菌复合群分离株进行菌种鉴定。
J Clin Microbiol. 2000 Feb;38(2):508-12. doi: 10.1128/JCM.38.2.508-512.2000.
本文引用的文献
1
Diagnosis and treatment of disease caused by nontuberculous mycobacteria. This official statement of the American Thoracic Society was approved by the Board of Directors, March 1997. Medical Section of the American Lung Association.非结核分枝杆菌所致疾病的诊断与治疗。本美国胸科学会官方声明于1997年3月经董事会批准。美国肺脏协会医学部。
Am J Respir Crit Care Med. 1997 Aug;156(2 Pt 2):S1-25. doi: 10.1164/ajrccm.156.2.atsstatement.
2
Biochemical and molecular analysis of phospholipase C and phospholipase D activity in mycobacteria.分枝杆菌中磷脂酶C和磷脂酶D活性的生化与分子分析
Infect Immun. 1996 Aug;64(8):3259-66. doi: 10.1128/iai.64.8.3259-3266.1996.
3
Genetic diversity among strains of Mycobacterium avium causing monoclonal and polyclonal bacteremia in patients with AIDS.在艾滋病患者中导致单克隆和多克隆菌血症的鸟分枝杆菌菌株之间的遗传多样性。
J Infect Dis. 1993 Jun;167(6):1384-90. doi: 10.1093/infdis/167.6.1384.
4
Disease due to the Mycobacterium avium complex in patients with AIDS: epidemiology and clinical syndrome.艾滋病患者鸟分枝杆菌复合群所致疾病：流行病学与临床综合征
Clin Infect Dis. 1994 Apr;18 Suppl 3:S218-22. doi: 10.1093/clinids/18.supplement_3.s218.
5
Polyclonal infections due to Mycobacterium avium complex in patients with AIDS detected by pulsed-field gel electrophoresis of sequential clinical isolates.通过对连续临床分离株进行脉冲场凝胶电泳检测艾滋病患者中鸟分枝杆菌复合群引起的多克隆感染。
J Clin Microbiol. 1994 Jul;32(7):1773-8. doi: 10.1128/jcm.32.7.1773-1778.1994.
6
Persistent colonisation of potable water as a source of Mycobacterium avium infection in AIDS.作为艾滋病患者鸟分枝杆菌感染源的饮用水持续定植。
Lancet. 1994 May 7;343(8906):1137-41. doi: 10.1016/s0140-6736(94)90239-9.
7
Treatment of refractory disseminated nontuberculous mycobacterial infection with interferon gamma. A preliminary report.用γ干扰素治疗难治性播散性非结核分枝杆菌感染：初步报告。
N Engl J Med. 1994 May 12;330(19):1348-55. doi: 10.1056/NEJM199405123301904.
8
A species-specific nucleotide sequence of Mycobacterium tuberculosis encodes a protein that exhibits hemolytic activity when expressed in Escherichia coli.结核分枝杆菌的一种物种特异性核苷酸序列编码一种蛋白质，该蛋白质在大肠杆菌中表达时具有溶血活性。
Infect Immun. 1995 Nov;63(11):4301-6. doi: 10.1128/iai.63.11.4301-4306.1995.
9
Disseminated infection with Mycobacterium avium-intracellulare. A report of 13 cases and a review of the literature.鸟分枝杆菌-胞内分枝杆菌播散性感染。13例报告及文献复习。
Medicine (Baltimore). 1985 Jan;64(1):36-48. doi: 10.1097/00005792-198501000-00003.
10
Infection with Mycobacterium avium complex in patients without predisposing conditions.无易感因素患者的鸟分枝杆菌复合群感染
N Engl J Med. 1989 Sep 28;321(13):863-8. doi: 10.1056/NEJM198909283211304.
Zotero 插件