Fahmy J A, Moller S, Bentzon M W
Acta Ophthalmol (Copenh). 1976 Jul;54(3):271-80. doi: 10.1111/j.1755-3768.1976.tb01255.x.
In 499 patients operated on for cataract, the clinical postoperative signs of extraocular inflammation (conjunctival hyperaemia, chemosis, discharge and oedema of the lids), the number of infiltrates around the corneoscleral sutures, and the severity of intraocular inflammation in the anterior chamber (aqueous-flare) were assessed on the fourth postoperative day and correlated with the bacterial conjunctival flora examined both qualitatively and quantitatively on the same day. Patients with potential pathogens (Staphylococcus aureus, gram-negative bacilli and streptococci) on the conjunctiva following operation did not show any increased inflammatory reactions when compared with those without such pathogen. The quantity of bacteria, i.e. number of colonies, did not appear to play a role. The reasons are discussed. The clinical postoperative inflammatory signs were further correlated with the following factors: surgical complications, quality of suturing technique, use of alpha chymotrypsin, systemic disease, sex and age. A positive correlation was found between the severity of extraocular inflammation and retained lens material and hyphaema. Furthermore, extraocular reactions were more severe in males than in females. The incidence of infiltrates around corneoscleral sutures was found to vary with age, i.e. occurred more frequently in patients less than 60 years. No relationship was found between the severity of aqueous-flare and the above mentioned factors.
对499例接受白内障手术的患者，在术后第4天评估其眼外炎症的临床体征（结膜充血、球结膜水肿、分泌物及眼睑水肿）、角膜巩膜缝线周围浸润灶的数量以及前房内眼内炎症的严重程度（房水闪光），并将这些指标与同一天定性和定量检测的结膜细菌菌群进行相关性分析。术后结膜存在潜在病原体（金黄色葡萄球菌、革兰氏阴性杆菌和链球菌）的患者，与无此类病原体的患者相比，并未表现出任何炎症反应增加的情况。细菌数量，即菌落数，似乎不起作用。文中对相关原因进行了讨论。术后临床炎症体征还与以下因素进行了进一步的相关性分析：手术并发症、缝合技术质量、α-糜蛋白酶的使用、全身疾病、性别和年龄。发现眼外炎症的严重程度与残留晶状体物质及前房积血之间呈正相关。此外，男性的眼外反应比女性更严重。发现角膜巩膜缝线周围浸润灶的发生率随年龄而异，即在60岁以下患者中更常见。未发现房水闪光的严重程度与上述因素之间存在关联。
