Harper M E, Danutra V, Chandler J A, Griffiths K
Acta Endocrinol (Copenh). 1976 Sep;83(1):211-24. doi: 10.1530/acta.0.0830211.
2-Bromo-alpha-ergocryptine (CB154) administration to male rats produced a significant decrease in plasma prolactin levels without changing the LH and testosterone concentrations. The weights of the accessory sex tissues, testes, adrenals and kidney were unaltered by the treatment. Zinc concentration and distribution in the cell organelles of the prostatic tissue was markedly changed by CB154 treatment. No changes in the uptake of testosterone in vivo occurred in the treated animals. Prolactin did not consistently influence the prostatic adenyl cyclase activity in vitro and only at high concentrations was the testosterone uptake in vitro with cultures of prostatic tissue increased.
给雄性大鼠注射2-溴-α-麦角隐亭（CB154）可使血浆催乳素水平显著降低，而不改变促黄体生成素（LH）和睾酮浓度。附属生殖器官、睾丸、肾上腺和肾脏的重量不受该处理影响。CB154处理显著改变了前列腺组织细胞器中的锌浓度和分布。经处理的动物体内睾酮摄取无变化。催乳素在体外对前列腺腺苷酸环化酶活性的影响并不一致，仅在高浓度时，前列腺组织培养物的体外睾酮摄取量增加。
