Chim C S, Ho P L, Yuen S T, Yuen K Y
Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong.
J Infect. 1998 Nov;37(3):287-91. doi: 10.1016/s0163-4453(98)92169-7.
We report a case of fungal endocarditis due to Aspergillus terreus in a leukaemia patient who received a bone marrow allograft from a matched unrelated donor. He presented with persistent fever. microangiopathic haemolytic anaemia but there was no cardiac signs and symptoms. He died despite intravenous amphotericin B. Review of the English literature showed five other patients with fungal endocarditis in the setting of bone marrow transplantation and revealed the same features of difficult diagnosis and poor outcome.
我们报告了一例白血病患者发生土曲霉引起的真菌性心内膜炎的病例，该患者接受了来自匹配的无关供体的骨髓同种异体移植。他出现持续发热、微血管病性溶血性贫血，但无心脏体征和症状。尽管静脉注射了两性霉素B，他仍死亡。对英文文献的回顾显示，另外还有5例骨髓移植患者发生真菌性心内膜炎，且具有诊断困难和预后不良的相同特征。
