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[子宫肌瘤和子宫内膜异位症女性的血液及子宫组织糖原含量(作者译)]

[The glycogen content of blood and uterine tissue in women with myoma and endometriosis (author's transl)].

作者信息

Muck B R, Hommel G

出版信息

Arch Gynakol. 1976 Sep 17;221(2):129-37. doi: 10.1007/BF00667142.

Abstract

The amount of glycogen in venous blood and uterine tissue from 135 women undergoing gynecologic surgery was quantitatively determined. One group had myoma (n = 48), another endometriosis (n = 30). 18 women had myoma combined with endometriosis of the myometrium. 39 women served as control group. The following samples of the uterus were obtained immediately after removal: endometrium, myometrium, cervix and "tumour". The glycogen content in pathological cases was compared to normal tissue of comparative endocrine state, parity status and glucose tolerance. The significance levels were determined by standard analysis of variance and "t" tests. In the group with endometriosis, a significant difference occurred in the amount of blood glycogen, while a significant decrease was observed in the myometrial tissue. The cervical tissue glycogen levels of patients with myoma or endometriosis were significantly higher and did not exhibit cyclic or menopausal changes. There were no significant cyclic differences in the amount of endometrial tissue glycogen in women with myoma or endometriosis. In these cases the glycogen content was significantly higher than in healthy endometrial tissue. Blood glucose and plasma insulin levels were found to be in a normal spectrum. Pathological glucose tolerance and parity status showed no correlation to the variation of uterine tissue glycogen.

摘要

对135名接受妇科手术的女性的静脉血和子宫组织中的糖原含量进行了定量测定。一组患有肌瘤(n = 48),另一组患有子宫内膜异位症(n = 30)。18名女性患有肌瘤合并子宫肌层子宫内膜异位症。39名女性作为对照组。子宫切除后立即获取以下子宫样本:子宫内膜、子宫肌层、宫颈和“肿瘤”。将病理病例中的糖原含量与具有可比内分泌状态、产次状况和糖耐量的正常组织进行比较。显著性水平通过标准方差分析和“t”检验确定。在患有子宫内膜异位症的组中,血糖原含量出现显著差异,而子宫肌层组织中观察到显著降低。患有肌瘤或子宫内膜异位症的患者宫颈组织糖原水平显著更高,且未表现出周期性或绝经变化。患有肌瘤或子宫内膜异位症的女性子宫内膜组织糖原含量无显著周期性差异。在这些病例中,糖原含量显著高于健康子宫内膜组织。发现血糖和血浆胰岛素水平在正常范围内。病理性糖耐量和产次状况与子宫组织糖原变化无相关性。

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