Verhaegen H, De Cock W, De Cree J, Verbruggen F
Cancer. 1976 Oct;38(4):1608-13. doi: 10.1002/1097-0142(197610)38:4<1608::aid-cncr2820380427>3.0.co;2-6.
Complement levels (CH50, C3, C4 and C1q) were determined in sera of 90 healthy subjects and 200 cancer patients. Complement levels of cancer patients were significantly higher than those of the healthy subjects, but there was a stage-linked increase of complement levels. Patients in remission had nearly normal complement levels, but patients with local tumor had increased complement levels, and a further increase was observed in patients with distant metastases. Treatment of these patients with radiotherapy or cytostatic drugs lowered the complement levels. At the terminal phase of the disease we also noted a drop in complement levels.
对90名健康受试者和200名癌症患者的血清进行补体水平（CH50、C3、C4和C1q）测定。癌症患者的补体水平显著高于健康受试者，且补体水平存在分期相关的升高。缓解期患者的补体水平接近正常，但局部肿瘤患者的补体水平升高，远处转移患者的补体水平进一步升高。用放疗或细胞抑制药物治疗这些患者可降低补体水平。在疾病终末期，我们还注意到补体水平下降。
