Wohlert S E, Künzel E, Machinek R, Méndez C, Salas J A, Rohr J
Medical University of South Carolina, Department of Pharmaceutical Sciences, 171 Ashley Avenue, Charleston, South Carolina 29425-2303, USA.
J Nat Prod. 1999 Jan;62(1):119-21. doi: 10.1021/np980355k.
A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3being confirmed for mithramycin.
据报道，对产自链霉菌ATCC 12956的主要产物光神霉素的结构进行了重新研究。使用包括全相关谱（TOCSY）、异核多键相关谱（HMBC）和异核单量子相关谱（HSQC）实验在内的二维核磁共振方法，对光神霉素十乙酸酯（4）进行了结构解析。该研究结果证实了光神霉素的结构为3。
