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多发性硬化症与麻疹:细胞致敏作用研究

Multiple sclerosis and measles: a study of cellular sensitization.

作者信息

Field E J, Shenton B K

出版信息

Eur Neurol. 1976;14(6):401-7. doi: 10.1159/000114766.

Abstract

Lymphocyte sensitization to measles has been studied in comparable groups of multiple sclerosis, other neurologic disease and normal subjects. The macrophage electrophoretic mobility test has been used. No difference between the three groups has been found, though there is a small group of children with obscure neurological disease which might well be multiple sclerosis and which fails to mount an adequate response to measles. The role of measles (and other banal infections) in aetiopathogenesis of multiple sclerosis is briefly discussed.

摘要

在患有多发性硬化症、其他神经系统疾病的可比组以及正常受试者中,对麻疹的淋巴细胞致敏情况进行了研究。采用了巨噬细胞电泳迁移率试验。尽管有一小群患有不明神经系统疾病的儿童很可能是多发性硬化症患者,且对麻疹未能产生充分反应,但三组之间未发现差异。本文简要讨论了麻疹(以及其他常见感染)在多发性硬化症病因发病机制中的作用。

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