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关于多发性硬化症的病因发病机制,麻疹病毒与致脑炎因子的关系。

Relation of measles virus to encephalitogenic factor with reference to the aetiopathogenesis of multiple sclerosis.

作者信息

McDermott J R, Field E J, Caspary E A

出版信息

J Neurol Neurosurg Psychiatry. 1974 Mar;37(3):282-7. doi: 10.1136/jnnp.37.3.282.

Abstract

A combination of affinity chromatography with the macrophage electrophoretic migration (MEM) test has been used to study the antigenic similarities between encephalitogenic factor (EF) and measles virus. These have determinant(s) sufficiently closely related to account for the elevated level of circulating antibody to measles in multiple sclerosis.

摘要

亲和层析与巨噬细胞电泳迁移率(MEM)试验相结合,已被用于研究致脑炎因子(EF)与麻疹病毒之间的抗原相似性。这些因子具有足够紧密相关的决定簇,以解释多发性硬化症中针对麻疹的循环抗体水平升高的原因。

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