Boer J, van Gemert M J
Department of Dermatology, Deventer Hospital, The Netherlands.
J Am Acad Dermatol. 1999 Jan;40(1):73-6. doi: 10.1016/s0190-9622(99)70530-x.
Oral isotretinoin has been used to treat mild to severe hidradenitis suppurativa (HS).
We reviewed the results of low-dose isotretinoin for 4 to 6 months in the treatment of 68 patients with HS.
This is a retrospective study. Data are presented in terms of response rate, long-term follow-up, and the relation between response rate and severity.
In 16 patients (23.5%), the condition completely cleared during initial therapy and 11 patients (16.2%) maintained their improvement during the follow-up period. Treatment was more successful in the milder forms of HS.
Monotherapy with isotretinoin for patients with HS usually has a limited therapeutic effect.
口服异维A酸已被用于治疗轻度至重度化脓性汗腺炎（HS）。
我们回顾了低剂量异维A酸治疗68例HS患者4至6个月的结果。
这是一项回顾性研究。数据以缓解率、长期随访以及缓解率与严重程度之间的关系呈现。
16例患者（23.5%）在初始治疗期间病情完全缓解，11例患者（16.2%）在随访期间病情持续改善。HS病情较轻的患者治疗效果更佳。
异维A酸单药治疗HS患者通常疗效有限。
