参与鸡红细胞抗体依赖性细胞介导裂解的抗体类别。
The class of antibody involved in the antibody-dependent cell-mediated lysis of chicken erythrocytes.
作者信息
Macphail S
出版信息
Immunology. 1976 Nov;31(5):697-705.
Abstract
Affinity chromatographic experiments demonstrated that IgG was the class of antibody involved in the in vitro lysis of chicken erythrocytes by antibody and normal mouse effector cells. Further experiments designed to investigate the subclass of IgG involved, indicated that IgG2a was active and provided further evidence for the inactivity of IgM, either in the native 19S or chemically degraded 7S form. From the results obtained, the possibility of ADCC-inducing activity in the other IgG subclasses could not be excluded.
摘要
亲和色谱实验表明，IgG是参与抗体和正常小鼠效应细胞在体外裂解鸡红细胞的抗体类别。旨在研究相关IgG亚类的进一步实验表明，IgG2a具有活性，并为IgM无论是天然19S形式还是化学降解的7S形式均无活性提供了进一步证据。从获得的结果来看，不能排除其他IgG亚类具有ADCC诱导活性的可能性。
相似文献
1
The class of antibody involved in the antibody-dependent cell-mediated lysis of chicken erythrocytes.参与鸡红细胞抗体依赖性细胞介导裂解的抗体类别。
Immunology. 1976 Nov;31(5):697-705.
2
3
All classes of murine IgG antibody mediate macrophage phagocytosis and lysis of erythrocytes.所有类别的小鼠IgG抗体都介导巨噬细胞对红细胞的吞噬作用和裂解作用。
J Immunol. 1980 Nov;125(5):1885-8.
4
Antibody-dependent cell-mediated cytotoxicity. II. Early interactions between effector and target cells.抗体依赖性细胞介导的细胞毒性。II. 效应细胞与靶细胞之间的早期相互作用。
J Immunol. 1974 Nov;113(5):1519-26.
5
Role of antibody and complement in the immune clearance and destruction of erythrocytes. II. Molecular nature of IgG and IgM complement-fixing sites and effects of their interaction with serum.抗体和补体在红细胞免疫清除与破坏中的作用。II. IgG和IgM补体结合位点的分子性质及其与血清相互作用的影响
J Clin Invest. 1972 Mar;51(3):583-9. doi: 10.1172/JCI106847.
6
Interaction of K lymphocytes with myeloma proteins of different IgG subclasses.K淋巴细胞与不同IgG亚类骨髓瘤蛋白的相互作用。
J Immunol. 1976 Nov;117(5 Pt 1):1464-71.
7
8
9
Antibody-dependent cytolysis of chicken erythrocytes by an in vitro-established line of mouse peritoneal macrophages.体外建立的小鼠腹腔巨噬细胞系对鸡红细胞的抗体依赖性细胞溶解作用。
J Immunol. 1975 Feb;114(2 pt 2):765-9.
引用本文的文献
1
Lack of evidence for IgM-induced ADCC: studies with monoclonal and polyclonal antibodies.缺乏IgM诱导的抗体依赖性细胞介导的细胞毒性的证据：单克隆和多克隆抗体研究
Immunology. 1981 May;43(1):161-70.
本文引用的文献
1
Contactual lysis of antibody-coated chicken erythrocytes by purified lymphocytes.纯化淋巴细胞对抗体包被的鸡红细胞的接触性溶解作用。
Cell Immunol. 1970 Sep;1(3):300-15. doi: 10.1016/0008-8749(70)90051-1.
2
Antibody-mediated target cell lysis by non-immune cells. Characterization of the antibody and effector cell populations.非免疫细胞介导的抗体依赖性靶细胞裂解。抗体和效应细胞群体的特征分析。
Eur J Immunol. 1972 Oct;2(5):419-24. doi: 10.1002/eji.1830020507.
3
Characterization of the antibody-dependent cytotoxic cell. A non-phagocytic monocyte?抗体依赖性细胞毒性细胞的特性。一种非吞噬性单核细胞？
Clin Exp Immunol. 1973 Oct;15(2):251-9.
4
Cellular immunity to heterologous erythrocytes in vitro. I. The role of surface-adherent cells and specific mediators in an effector mechanism.体外对异种红细胞的细胞免疫。I. 表面黏附细胞和特异性介质在效应机制中的作用。
Cell Immunol. 1973 May;7(2):222-36. doi: 10.1016/0008-8749(73)90245-1.
5
Lymphocyte mediated cytotoxicity in vitro. Induction and inhibition by humoral antibody and nature of effector cells.体外淋巴细胞介导的细胞毒性。体液抗体的诱导和抑制作用以及效应细胞的性质。
Transplant Rev. 1972;13:91-114. doi: 10.1111/j.1600-065x.1972.tb00061.x.
6
Lymphocyte-mediated cytotoxicity and blocking serum activity to tumor antigens.淋巴细胞介导的细胞毒性作用以及针对肿瘤抗原的封闭血清活性
Adv Immunol. 1974;18:209-77. doi: 10.1016/s0065-2776(08)60311-9.
7
Antibody in the induction and inhibition of lymphocyte cytotoxicity.抗体在淋巴细胞细胞毒性的诱导和抑制中的作用。
Transplant Rev. 1972;13:67-90. doi: 10.1111/j.1600-065x.1972.tb00060.x.
8
Immunological tumor enhancement and in vitro cytotoxicity. Further evidence for the involvement of 7S 2a-immunoglobulin.
Transplantation. 1973 Sep;16(3):171-6. doi: 10.1097/00007890-197309000-00002.
9
Zotero 插件