Smith C A, Pepose J S
Department of Ophthalmology and Visual Science, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Am J Ophthalmol. 1999 Jan;127(1):77-84. doi: 10.1016/s0002-9394(98)00414-0.
To determine whether routine office techniques used to disinfect tonometer prisms and trial contact lenses are sufficient to prevent transmission of ocular infections.
We reviewed the current literature on the efficacy of certain disinfection protocols against commonly encountered viral, bacterial, and fungal pathogens as well as Acanthamoeba.
Some commonly used disinfecting solutions and techniques may be inadequate for disinfection of viruses such as hepatitis C virus and organisms such as Acanthamoeba. When used in accordance with guidelines published by the United States Centers for Disease Control and Prevention (CDC) and the American Academy of Ophthalmology (AAO), 3% hydrogen peroxide is a very effective disinfectant against a wide variety of microorganisms. Specifically, tonometer prisms disinfected by a 5-minute soak in 3% hydrogen peroxide (or 70% isopropyl alcohol or a 1:10 dilution of sodium hypochlorite) are adequately disinfected against most ocular pathogens, with the exception of Acanthamoeba. Trial contact lenses that are disinfected with a 2-hour soak in 3% hydrogen peroxide are effectively rid of all pathogens of concern. After disinfection, rigid lenses should be stored dry, and soft lenses should be stored in a sterile, preserved solution. Repeat disinfection should be routinely performed at 1-month intervals to prevent regrowth of organisms.
A safe office environment can be maintained by following current CDC recommendations for disinfection, as well as instituting some additional procedures.
确定用于消毒眼压计棱镜和试验性隐形眼镜的常规办公室技术是否足以预防眼部感染的传播。
我们回顾了当前关于某些消毒方案对常见病毒、细菌、真菌病原体以及棘阿米巴的有效性的文献。
一些常用的消毒溶液和技术可能不足以对丙型肝炎病毒等病毒以及棘阿米巴等生物体进行消毒。按照美国疾病控制与预防中心(CDC)和美国眼科学会(AAO)发布的指南使用时,3%过氧化氢是一种对多种微生物非常有效的消毒剂。具体而言,眼压计棱镜在3%过氧化氢中浸泡5分钟(或70%异丙醇或1:10稀释的次氯酸钠)进行消毒后,除棘阿米巴外,对大多数眼部病原体均能充分消毒。试验性隐形眼镜在3%过氧化氢中浸泡2小时进行消毒后,能有效清除所有相关病原体。消毒后,硬性隐形眼镜应干燥保存,软性隐形眼镜应保存在无菌的保存液中。应定期每隔1个月进行重复消毒,以防止生物体再生。
遵循CDC当前的消毒建议并制定一些额外程序,可以维持一个安全的办公室环境。