Hwang J M, Girkin C A, Perry J D, Lai J C, Miller N R, Hellmann D B
Neuro-Ophthalmology Unit, Wilmer Eye Institute, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.
Am J Ophthalmol. 1999 Jan;127(1):102-4. doi: 10.1016/s0002-9394(98)00313-4.
To report the development of a bilateral ocular ischemic syndrome despite corticosteroid treatment in a patient with giant cell arteritis.
Case report.
Despite receiving high-dose intravenous methylprednisolone and oral prednisone for biopsy-proven giant cell arteritis that presented as a severe anterior ischemic optic neuropathy in the right eye, a patient developed progressive ocular ischemia in that eye as well as an ocular ischemic syndrome in the fellow eye.
Some patients with giant cell arteritis, possibly patients with other underlying systemic vasculopathies, are refractory to what should be adequate treatment with systemic corticosteroids and may develop a bilateral ocular ischemic syndrome.
报告1例巨细胞动脉炎患者在接受皮质类固醇治疗后仍发生双侧眼部缺血综合征的情况。
病例报告。
1例经活检证实为巨细胞动脉炎的患者，以右眼严重前部缺血性视神经病变为表现，尽管接受了大剂量静脉注射甲泼尼龙和口服泼尼松治疗，但右眼仍出现进行性眼部缺血，对侧眼也出现了眼部缺血综合征。
一些巨细胞动脉炎患者，可能还有其他潜在系统性血管病变的患者，对本应充分的全身皮质类固醇治疗无效，可能会发展为双侧眼部缺血综合征。
