Ruza Paz-Curbera E, Fernández Benítez M
Department of Pediatrics, University of Clinic of Navarra, Faculty of Medicine, Pamplona, Spain.
Allergol Immunopathol (Madr). 1998 Nov-Dec;26(6):291-3.
The Melkersson-Rosenthal syndrome (MRS) consists of recurrent edema of the lips, intermittent facial palsy and furrowed tongue. This is the classic triad which defines the syndrome, although it is accepted that the presence of two manifestations or one with a granulomatous cheilitis in the biopsy, are sufficient to make the diagnosis. The case of a 15 year-old diabetic boy is presented. He had a persistent edema of the upper lip of one-year duration, which started abruptly without any clear etiologic correlation. He was treated with antihistaminics and corticosteroids without improvement but with diabetic imbalance. The complementary examinations were normal and the biopsy was compatible with granulomatous cheilitis. Despite the low incidence and the fact that there is no specific treatment, MRS has to be considered as a diagnostic possibility in a patient with recurrent edema although not necessarily having the complete triad.
梅尔克森 - 罗森塔尔综合征（MRS）由唇部反复水肿、间歇性面瘫和舌面沟裂组成。这是定义该综合征的经典三联征，不过，活检显示存在两种表现或一种伴有肉芽肿性唇炎，也足以做出诊断。本文介绍了一名15岁糖尿病男孩的病例。他上唇持续水肿长达一年，起病突然，无明显病因关联。他接受了抗组胺药和皮质类固醇治疗，但病情无改善，反而出现糖尿病失衡。辅助检查正常，活检结果符合肉芽肿性唇炎。尽管MRS发病率低且无特异性治疗方法，但对于反复水肿的患者，即使不一定具备完整的三联征，也必须考虑将MRS作为一种诊断可能性。
