Pour P, Mohr U, Altoff J, Cardesa A, Kmoch N
J Natl Cancer Inst. 1976 May;56(5):963-74. doi: 10.1093/jnci/56.5.963.
Spontaneous tumors were found in the vascular and lymphatic systems upon systemic histologic examination of the cardiovascular, hematopoietic, and lymphatic tissues of Syrian hamsters from the Eppley (EC) and Hannover colonies (HC). The incidence of endothelial tumors (hemangioendotheliomas) was similar in both colonies and sexes. The hemangioendotheliomas generally originated in the liver and spleen. Malignant lymphomas developed in high incidences in both colonies; however, their morphology varied. Those in EC hamsters were of histiocytic and, to a lesser extent, plasmacytic types; in the HC lymphocytic and epithelioid cell types were also found. Among tumors of miscellaneous sites, Harderian gland adenomas occurred in almost equal frequencies in EC and HC hamsters, but predominated in males. Tumors of the bone and soft tissue were present only in EC hamsters, whereas skin neoplasms developed solely in HC hamsters.
对来自埃普利（EC）和汉诺威（HC）种群的叙利亚仓鼠的心血管、造血和淋巴组织进行全身组织学检查时，在血管和淋巴系统中发现了自发性肿瘤。两个种群以及不同性别的内皮细胞瘤（血管内皮瘤）发病率相似。血管内皮瘤通常起源于肝脏和脾脏。两个种群中恶性淋巴瘤的发病率都很高；然而，它们的形态有所不同。EC仓鼠中的淋巴瘤为组织细胞型，在较小程度上为浆细胞型；在HC仓鼠中还发现了淋巴细胞型和上皮样细胞型。在其他部位的肿瘤中，哈德氏腺腺瘤在EC和HC仓鼠中的发生率几乎相同，但在雄性中占主导地位。骨和软组织肿瘤仅出现在EC仓鼠中，而皮肤肿瘤仅在HC仓鼠中发生。
