Pour P, Mohr U, Althoff J, Cardesa A, Kmoch N
J Natl Cancer Inst. 1976 May;56(5):949-61. doi: 10.1093/jnci/56.5.949.
The frequency of spontaneously occuring neoplasms in the urogenital system and endocrine organs was examined in two Syrian hamster colonies [Eppley colony (EC); Hannover colony (HC)]. With the exception of a renal adenoma in an EC female, the urinary systems of animals in both colonies were free of neoplastic growths. A single epididymal adenoma of the male fenital system (EC) was found. However, incidences of female genital tract tumors were 10 (EC) and 3.5% (HC) and accounted for 34 and 11%, respectively, of all tumors in females. Among all genital tract tumors, 3 (EC) and 57% (HC) were ovarian, 14% (HC) were in the fallopian tubes, 81 (EC) AND 29% (HC) were uterine, and 16% (EC), vaginal. The overall incidence of endocrine organ tumors was similar in both colonies (EC, 22%; HC, 19%). The distribution of these tumors was as follows: pituitary gland; EC, 3%, HC, 0; thyroid gland: EC, 28%, HC, 31%; parathyroid gland: EC,11%, HC, 18%; adrenal cortex: EC, 42%, HC, 31%; adrenal medulla: EC, 7%, HC, 0; and endocrine pancreas: EC, 10%, HC, 31%. The morphology of these neoplasms is described and the incidence compared with those reported in other colonies.
在两个叙利亚仓鼠群体[埃普利群体（EC）；汉诺威群体（HC）]中，对泌尿生殖系统和内分泌器官中自发出现的肿瘤频率进行了检查。除了一只EC群体的雌性仓鼠患有肾腺瘤外，两个群体的动物泌尿系统均无肿瘤生长。在雄性生殖系统中发现了一例附睾腺瘤（EC群体）。然而，雌性生殖道肿瘤的发生率在EC群体中为10%，在HC群体中为3.5%，分别占雌性所有肿瘤的34%和11%。在所有生殖道肿瘤中，卵巢肿瘤在EC群体中占3%，在HC群体中占57%；输卵管肿瘤在HC群体中占14%；子宫肿瘤在EC群体中占81%，在HC群体中占29%；阴道肿瘤在EC群体中占16%。两个群体中内分泌器官肿瘤的总体发生率相似（EC群体为22%；HC群体为19%）。这些肿瘤的分布如下：垂体：EC群体为3%，HC群体为0；甲状腺：EC群体为28%，HC群体为31%；甲状旁腺：EC群体为11%，HC群体为18%；肾上腺皮质：EC群体为42%，HC群体为31%；肾上腺髓质：EC群体为7%，HC群体为0；内分泌胰腺：EC群体为10%，HC群体为31%。本文描述了这些肿瘤的形态，并将发生率与其他群体报告的发生率进行了比较。
