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[腹腔镜检查能否降低不必要阑尾切除术的发生率?]

[Does laparoscopy reduce the incidence of useless appendectomies?].

作者信息

Barrat C, Champault G, Catheline J M, Rizk N, Ziol M, Guettier C

机构信息

Service de Chirurgie Générale et Digestive, Hôpital Jean-Verdier, Bondy.

出版信息

Ann Chir. 1998;52(10):965-9.

PMID:9951095
Abstract

The aim of this retrospective study is to evaluate the impact of laparoscopic appendicectomy on the incidence of histologically normal appendices. Between 1987 and 1997, 1220 consecutives patients--with an average age of 23.5 years (17-73) and including 841 women (69%)--underwent appendicectomy due to the presence of at least one of the following 3 criteria: right iliac fossa guarding, fever greater than 38 degrees C and hyperleucocytosis greater than 10,000. Patients were divided into two group.: First group with 930 patients were operated by laparotomy and the other group of 355 patients underwent laparoscopic exploration with appendicectomy when macroscopic abnormalities were observed (290 cases). In all cases, the appendices were examined under blind conditions and classified as normal or pathological, and were subsequently classified according to the nature and the severity of the lesions. In group I (laparotomy), the incidence of histologically normal appendices was 25.1%. In group II (laparoscopic), this incidence was only 8.2%. The difference was significant (p = 0.015). In 65 cases (18.3%), a macroscopically normal appendix was left in place: in 55 cases the symptoms were due to another identified cause, however, in 10 cases no cause was found. This study suggests that laparoscopy significantly reduces the number of histologically normal appendices because an other cause is identified more easily provided macroscopically normal appendices are not removed with a small proportion (5-10%) cases of early appendicitis with only mucosal involvement. In the absence of other causes for the symptoms, a three-day course of antibiotics can be tried in order to treat possible mucosal lesions. This approach reduces costs without having any adverse consequences on outcome.

摘要

这项回顾性研究的目的是评估腹腔镜阑尾切除术对组织学上正常阑尾发生率的影响。1987年至1997年间,1220例连续患者(平均年龄23.5岁,17 - 73岁,其中841例为女性,占69%)因出现以下3项标准中至少1项而接受阑尾切除术:右下腹压痛、体温高于38摄氏度以及白细胞增多超过10000。患者分为两组:第一组930例患者接受开腹手术,另一组355例患者在观察到宏观异常时(290例)接受腹腔镜探查并进行阑尾切除术。在所有病例中,阑尾在盲视条件下进行检查,分为正常或病理状态,随后根据病变的性质和严重程度进行分类。在第一组(开腹手术组)中,组织学上正常阑尾的发生率为25.1%。在第二组(腹腔镜组)中,该发生率仅为8.2%。差异具有统计学意义(p = 0.015)。在65例(18.3%)病例中,肉眼正常的阑尾被保留:55例中症状是由另一个已确定的原因引起的,然而,在10例中未发现原因。这项研究表明,腹腔镜检查显著减少了组织学上正常阑尾的数量,因为如果肉眼正常的阑尾不被切除,且只有一小部分(5 - 10%)仅累及黏膜的早期阑尾炎病例,更容易确定其他原因。在没有其他症状原因的情况下,可以尝试使用三天疗程的抗生素来治疗可能的黏膜病变。这种方法在不影响治疗结果的情况下降低了成本。

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