Haraldsson Hjortur, Rosmundsson Thrainn, Oskarsson Kristjan, Jonasson Jon Gunnlaugur, Haraldsson Asgeir
Laeknabladid. 2008 Sep;94(9):599-604.
Appendicitis is a common disease and can be life-threatening if not adequately treated. Studies have shown that if less than 20% of appendices removed are normal it indicates missing or delaying the diagnosis of appendicitis, resulting in an increased incidence of perforation. The purpose of this study was to analyze appendicitis in children during two separate time periods in the pediatric wards of the hospitals in Reykjavík and to increase our knowledge of appendicitis in children in the country.
Patients entering this study are two groups of 100 children (< or =16 years) consecutively undergoing appendectomy in the Reykjavik hospitals, one group in 1996 and the other in 2006. Data on sex, age, clinical symptoms and treatment was obtained from patients records. The impression of the surgeon at time of operation on the inflammation of the removed appendix was compared with results of histopathology analysis. All histopathology slides from appendices from 2006 were re-evaluated. The parameters in open appendectomies were compared to those in laparoscopic appendectomies. The two study periods were compared.
The proportion of normal appendices was similar in both periods of the study, 18% in 2006 and 20% in 1996. The appendices were more often normal in female patients (p<0.05) and the large majority of those were removed by laparoscopic surgery. Perforation was present in 17% of inflamed appendices in both study groups. The time from patients arrival to hospital until surgery surpassed 10 hours in only one case in each study group. A discrepancy between the surgeon's assessment and the pathology result was noted only once in 2006 and in one additional case was the histopathological diagnosis altered following re-evaluation of the pathology slides.
The proportion of non-inflamed appendices in appendectomies in children in Reykjavik is in accordance with that reported elsewhere and perforation is not common. There is a good concordance between surgical and pathological assessment with regard to inflammation of the appendices.
阑尾炎是一种常见疾病,若治疗不充分可能危及生命。研究表明,如果切除的阑尾中正常阑尾比例低于20%,则表明存在阑尾炎漏诊或诊断延误,导致穿孔发生率增加。本研究的目的是分析雷克雅未克医院儿科病房两个不同时间段内儿童阑尾炎的情况,并增进我们对该国儿童阑尾炎的了解。
本研究的患者为两组各100名儿童(年龄≤16岁),他们在雷克雅未克医院连续接受阑尾切除术,一组在1996年,另一组在2006年。从患者记录中获取性别、年龄、临床症状和治疗的数据。将手术时外科医生对切除阑尾炎症的判断与组织病理学分析结果进行比较。对2006年阑尾的所有组织病理学切片进行重新评估。将开腹阑尾切除术的参数与腹腔镜阑尾切除术的参数进行比较。对两个研究时间段进行比较。
在研究的两个时间段内,正常阑尾的比例相似,2006年为18%,1996年为20%。女性患者的阑尾更常为正常(p<0.05),其中绝大多数是通过腹腔镜手术切除的。两个研究组中,17%的发炎阑尾存在穿孔。每个研究组中只有1例患者从入院到手术的时间超过10小时。2006年外科医生的评估与病理结果之间仅出现1次差异,在对病理切片重新评估后,另有1例改变了组织病理学诊断。
雷克雅未克儿童阑尾切除术中非发炎阑尾的比例与其他地方报道的一致,穿孔并不常见。在阑尾炎症方面,手术评估与病理评估之间具有良好的一致性。