Kiyosawa M, Baba T
Department of Ophthalmology, Tokyo Medical and Dental University, School of Medicine, Japan.
Int J Cardiol. 1998 Oct 1;66 Suppl 1:S141-7; discussion S149. doi: 10.1016/s0167-5273(98)00162-4.
We examined 65 (61 female and 4 male) Takayasu patients. Patient age ranged from 17 to 78 years old (mean 50.2); age of onset was from 11 to 60 years old (mean 32.8); and duration from onset to referral ranged from 1 month to 43 years (mean 16.8 years). Routine ophthalmological examinations were performed. Fluorescein angiography, kinetic perimetry by Goldmann perimetry, static perimetry by Octopus 1-2-3, electroretinography (ERG), and measurements of central retinal arterial pressure were also performed, as appropriate. Major causes of impaired visual acuity (less than 16/20) were cataract. A few patients had low visual acuity caused by Takayasu disease itself. On the other hand, although not many complained of visual disturbance, about 35% of patients had subnormal visual functions. Because the visual deterioration may be based on ocular hypoperfusion, which may subsequently lead to more serious changes, regular ophthalmological examination for every Takayasu disease patient is recommended.
我们检查了65例（61例女性和4例男性）大动脉炎患者。患者年龄在17至78岁之间（平均50.2岁）；发病年龄在11至60岁之间（平均32.8岁）；从发病到转诊的病程为1个月至43年（平均16.8年）。进行了常规眼科检查。还酌情进行了荧光素血管造影、Goldmann视野计的动态视野检查、Octopus 1-2-3的静态视野检查、视网膜电图（ERG）以及视网膜中央动脉压测量。视力受损（低于16/20）的主要原因是白内障。少数患者的低视力由大动脉炎本身引起。另一方面，虽然抱怨视力障碍的患者不多，但约35%的患者存在视觉功能异常。由于视力恶化可能基于眼部灌注不足，这可能随后导致更严重的变化，因此建议对每位大动脉炎患者进行定期眼科检查。
