Hellgren L, Vincent J
Sabouraudia. 1976 Nov;14(3):243-9. doi: 10.1080/00362177685190361.
The predominant fatty acids (C10-C18) of dermatophytes were investigated by the Landsteiner-Draize test to establish their allergenicity. It was demonstrated that fatty acids can give rise to sensitization of delayed type in guinea pigs. The middle-chain fatty acids (C10-C12) showed a high allergenicity compared to the (C13-C18) acids with moderate to weak contact sensitizing properties. The fatty acids may act as contact sensitizers and, at least sometimes, be responsible for the skin lesions in dermatophytosis.
通过兰德施泰纳-德莱兹试验研究皮肤癣菌的主要脂肪酸(C10 - C18)以确定其致敏性。结果表明,脂肪酸可引起豚鼠迟发型致敏。与具有中度至弱接触致敏特性的(C13 - C18)酸相比,中链脂肪酸(C10 - C12)显示出高致敏性。脂肪酸可能作为接触致敏剂,并且至少在某些时候,是皮肤癣菌病中皮肤病变的原因。