Lamson S A, Kong B M, De Salva S J
Contact Dermatitis. 1982 May;8(3):200-3. doi: 10.1111/j.1600-0536.1982.tb04183.x.
D & C Yellow No. 11 was found to be a skin sensitizer in guinea pigs at an elicitation concentration of 10.0% in ethanol but not at 1.0 and 3.0%. Sensitization was induced with a 50% suspension in ethanol. D & C Yellow No. 10, the disodium salt of the mono- and disulfonic acids of D & C Yellow No. 11, was not a skin sensitizer nor was it capable of eliciting a response in the D & C Yellow No. 11-sensitized guinea pigs even at a challenge concentration of 10%. Two commercial products, a soap containing 0.015% D & C Yellow No. 11 and a shampoo containing 0.002% D & C Yellow No. 10 did not elicit a reaction in the D & C Yellow No. 11-sensitized guinea pigs.
在豚鼠中，当D&C黄11在乙醇中的激发浓度为10.0%时被发现是一种皮肤致敏剂，但在1.0%和3.0%时不是。用乙醇中的50%悬浮液诱导致敏。D&C黄10是D&C黄11的单磺酸和二磺酸的二钠盐，它既不是皮肤致敏剂，也不能在D&C黄11致敏的豚鼠中引发反应，即使激发浓度为10%。两种商业产品，一种含有0.015% D&C黄11的肥皂和一种含有0.002% D&C黄10的洗发水，在D&C黄11致敏的豚鼠中没有引发反应。
