Santos F R, Pandya A, Tyler-Smith C, Pena S D, Schanfield M, Leonard W R, Osipova L, Crawford M H, Mitchell R J
Departamento de Biologia Geral, ICB/UFMG, Caixa Postal 486, 31. 270-910 Belo Horizonte, MG, Brazil.
Am J Hum Genet. 1999 Feb;64(2):619-28. doi: 10.1086/302242.
Y chromosomal DNA polymorphisms were used to investigate Pleistocene male migrations to the American continent. In a worldwide sample of 306 men, we obtained 32 haplotypes constructed with the variation found in 30 distinct polymorphic sites. The major Y haplotype present in most Native Americans was traced back to recent ancestors common with Siberians, namely, the Kets and Altaians from the Yenissey River Basin and Altai Mountains, respectively. Going further back, the next common ancestor gave rise also to Caucasoid Y chromosomes, probably from the central Eurasian region. This study, therefore, suggests a predominantly central Siberian origin for Native American paternal lineages for those who could have migrated to the Americas during the Upper Pleistocene.
Y染色体DNA多态性被用于研究更新世时期男性向美洲大陆的迁徙。在一个来自全球的306名男性样本中，我们利用在30个不同多态性位点发现的变异构建了32种单倍型。大多数美洲原住民中存在的主要Y单倍型可追溯到与西伯利亚人共有的近代祖先，即分别来自叶尼塞河流域和阿尔泰山脉的凯特人和阿尔泰人。再往前追溯，下一个共同祖先也产生了可能来自欧亚大陆中部地区的高加索人Y染色体。因此，这项研究表明，对于那些可能在上新世晚期迁徙到美洲的人来说，美洲原住民父系血统主要起源于西伯利亚中部。
