Kniazeva Z N, Shavalov L P, Vermul M S
Zh Mikrobiol Epidemiol Immunobiol. 1978 Apr(4):27-30.
A good survival of brucellae in the organism with the development of a stable and prolonged immunity was noted in vaccination of guinea pigs with live brucella vaccine prepared from the Br. abortus strain 19-BA. Local reactions were weak, and no general reactions were observed. In using the jet method of vaccination with the injectors bpi-4 and bi-2 on a limited group of persons (194) the local and general untoward response was weak, but in immunological respect this method proved to be effective when the vaccine was administered in a dose of 2.5 x 10(8) of microbial cells. Jet method can be recommended for express vaccination against brucellosis.
在用从流产布鲁氏菌19-BA菌株制备的活布鲁氏菌疫苗对豚鼠进行接种时,发现布鲁氏菌在机体内存活良好,并产生了稳定而持久的免疫力。局部反应较弱,未观察到全身反应。在对有限的一组人员(194人)使用bpi-4和bi-2注射器进行喷射接种法时,局部和全身不良反应较弱,但在免疫学方面,当以2.5×10(8)个微生物细胞的剂量接种疫苗时,该方法被证明是有效的。喷射接种法可推荐用于布鲁氏菌病的快速接种。