Maibach H
Arch Dermatol. 1976 Sep;112(9):1289-91.
A patient had a chronic hand eczema, presumably as a manifestation of atopy. Treatment resistance appeared due to handling certain foods that produced burning and stinging in the chronically eczematous skin and not in otherwise normal skin. Selected tests for delayed hypersensitivity and for immediate hyper sensitivity on intact skin of the back produced negative results, but on chronically inflamed skin of the arm and back, application of the pertinent foods produced a wheal and flare response. On intact skin, scratch tests with the foods produced positive results. Intradermal tests with commercial antigens were negative. Avoidance of these foods, as contactants, led to resolution of the dermatitis. Reappraisal of the role of immediate-type hypersensitivity in chronic hand eczema is important.
一名患者患有慢性手部湿疹，推测是特应性的一种表现。由于接触某些食物后，慢性湿疹皮肤会出现灼痛和刺痛，而正常皮肤则不会，从而导致治疗抵抗。对背部完整皮肤进行的迟发型超敏反应和速发型超敏反应的特定测试结果为阴性，但在手臂和背部的慢性炎症皮肤处，涂抹相关食物会产生风团和潮红反应。在完整皮肤上，用这些食物进行划痕试验结果为阳性。用商业抗原进行皮内试验结果为阴性。避免接触这些作为接触原的食物后，皮炎得以缓解。重新评估速发型超敏反应在慢性手部湿疹中的作用很重要。
