Delaere P R, Vander Poorten V, Hermans R
Department of Otorhinolaryngology-Head and Neck Surgery, University Hospitals of Leuven, Belgium.
Ann Otol Rhinol Laryngol. 1999 Feb;108(2):143-6. doi: 10.1177/000348949910800207.
Vascularized segments of trachea were used to repair extended hemilaryngectomy defects in a rabbit model. The cervical trachea was revascularized in a first stage by a fascia flap. In a second stage, the cervical trachea was isolated and transformed into a patch that could be autotransplanted on a vascular carrier. The patches were used for the reconstruction of hemilaryngectomy defects including half of the cricoid. Two months after transplantation, the vascular and morphologic characteristics of the tracheal patches were examined with silicone dye angiography and magnetic resonance imaging. The tracheal patches showed a reliable blood supply when wrapped in vascularized fascia. The patches provided a functional reconstruction of hemicricolaryngectomy defects. It is concluded that autotransplantation of the trachea should be further explored as a potential means for extending the limits of conservation laryngeal surgery.
在兔模型中，使用带血管的气管段修复扩大半喉切除术缺损。第一阶段通过筋膜瓣对颈段气管进行血管重建。第二阶段，分离颈段气管并将其转变为可自体移植到血管载体上的补片。这些补片用于重建包括环状软骨一半在内的半喉切除术缺损。移植两个月后，用硅染料血管造影术和磁共振成像检查气管补片的血管和形态特征。当包裹在带血管的筋膜中时，气管补片显示出可靠的血供。这些补片为半环状喉切除术缺损提供了功能性重建。结论是，气管自体移植作为扩大保留喉手术范围的一种潜在手段，应进一步探索。
