Abbas P J, Brown C J, Shallop J K, Firszt J B, Hughes M L, Hong S H, Staller S J
Department of Speech Pathology and Audiology, University of Iowa, Iowa City, USA.
Ear Hear. 1999 Feb;20(1):45-59. doi: 10.1097/00003446-199902000-00005.
This study outlines a series of experiments using the neural response telemetry (NRT) system of the Nucleus CI24M cochlear implant to measure the electrically evoked compound action potential (EAP). The goal of this investigation was to develop a protocol that allows successful recording of the EAP in a majority of CI24M cochlear implant users.
Twenty-six postlingually deafened adults participated in this study. A series of experiments were conducted that allowed us to examine how manipulation of stimulation and recording parameters may affect the morphology of the EAP recorded using the Nucleus NRT system.
Results of this study show consistent responses on at least some electrodes from all subjects. Cross-subject and cross electrode variations in both the growth of the response and the temporal refractory properties of the response were observed. The range of stimulus and recording parameters that can be used to record the EAP with the Nucleus NRT system is described.
Using the protocol outlined in this study, it is possible to reliably record EAP responses from most subjects and for most electrodes in Nucleus CI24M cochlear implant users. These responses are robust and recording these responses does not require that the subject sleep or remain still. Based on these results, a specific protocol is proposed for measurement of the EAP using the NRT system of the CI24M cochlear implant. Potential clinical implications of these results are discussed.
本研究概述了一系列使用Nucleus CI24M人工耳蜗的神经反应遥测（NRT）系统来测量电诱发复合动作电位（EAP）的实验。本研究的目的是制定一种方案，以便在大多数CI24M人工耳蜗使用者中成功记录EAP。
26名语后聋成年人参与了本研究。进行了一系列实验，使我们能够研究刺激和记录参数的操作如何影响使用Nucleus NRT系统记录的EAP的形态。
本研究结果显示，所有受试者至少在某些电极上有一致的反应。观察到不同受试者和不同电极在反应增长和反应的时间不应期特性方面存在差异。描述了可用于使用Nucleus NRT系统记录EAP的刺激和记录参数范围。
使用本研究中概述的方案，有可能在大多数受试者以及大多数Nucleus CI24M人工耳蜗使用者的电极上可靠地记录EAP反应。这些反应很稳定，记录这些反应并不要求受试者睡眠或保持静止。基于这些结果，提出了一种使用CI24M人工耳蜗的NRT系统测量EAP的具体方案。讨论了这些结果的潜在临床意义。
