Hays R B, Kegeles S M
Center for AIDS Prevention Studies, University of California, San Francisco, USA.
J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Feb 1;20(2):164-71. doi: 10.1097/00042560-199902010-00009.
Given their high seroincidence, young gay men will be targeted for recruitment into HIV vaccine trials but many challenges stand in the way of enlisting their cooperation. This study examined factors associated with young gay men's willingness to participate in vaccine trials and identified reasons for agreeing or not agreeing to participate. The data come from the Young Men's Survey, a cohort of western U.S. young gay men aged 18 to 29 years, surveyed using mail-back questionnaires. Participants who reported being HIV-negative or who had not been tested for HIV (n = 390) were asked to rate their desire to be given an HIV vaccine and their degree of willingness to participate in a vaccine trial. They also responded to open-ended questions regarding their reasons for participating or not participating. Of these respondents, 91% wanted to be given an HIV vaccine, yet many had serious reservations about participating in a vaccine trial. Men who had engaged in HIV risk behavior reported greater willingness to participate. The most common reasons for wanting to participate were desires to contribute to ending the AIDS epidemic and desire to help others; however, fears for one's own health and safety made many reluctant to participate.
鉴于年轻男同性恋者的血清学高发病率，他们将成为HIV疫苗试验招募的目标人群，但在争取他们合作的过程中存在诸多挑战。本研究调查了与年轻男同性恋者参与疫苗试验意愿相关的因素，并确定了同意或不同意参与的原因。数据来自“青年男性调查”，这是一组年龄在18至29岁的美国西部年轻男同性恋者，通过邮寄问卷进行调查。报告HIV检测呈阴性或未进行过HIV检测的参与者（n = 390）被要求对接受HIV疫苗的意愿以及参与疫苗试验的意愿程度进行评分。他们还回答了关于参与或不参与原因的开放式问题。在这些受访者中，91%希望接种HIV疫苗，但许多人对参与疫苗试验持严重保留态度。有过HIV风险行为的男性表示更愿意参与。希望参与的最常见原因是渴望为终结艾滋病流行做出贡献以及渴望帮助他人；然而，对自身健康和安全的担忧使许多人不愿参与。
