中国男男性行为者参与 HIV 疫苗临床试验的意愿。
Willingness to participate in HIV vaccine clinical trials among Chinese men who have sex with men.
机构信息
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS/STD Control and Prevention (NCAIDS), Chinese Center for Disease Control and Prevention (China CDC), Beijing 100050, PR China.
出版信息
Vaccine. 2010 Jun 23;28(29):4638-43. doi: 10.1016/j.vaccine.2010.04.073. Epub 2010 May 7.
HIV vaccine trials require volunteers. Little is known about willingness to participate (WTP) in HIV vaccine trials among Chinese MSM. A survey of 550 MSM was conducted from March to June 2008, in Beijing, China. Data were collected on demographics, behaviors, perceptions about HIV/AIDS and HIV vaccines, and concerns about participation in HIV vaccine clinical trials. Of study participants, 35.8% were definitely willing to participate, 35.1% were probably willing, 16.4% were probably not willing, and 12.7% were definitely not willing. Analyses suggest that perceived family support, perceived protection against HIV infection and fear that participation would result in social distancing were associated with WTP. MSM in China may be good candidates for HIV vaccine trials. Further studies are needed to evaluate actual enrollment.
HIV 疫苗试验需要志愿者。目前对于中国男男性行为者（MSM）对参与 HIV 疫苗试验的意愿（WTP）知之甚少。2008 年 3 月至 6 月期间，在中国北京对 550 名 MSM 进行了一项调查。收集的数据包括人口统计学、行为、对 HIV/AIDS 和 HIV 疫苗的看法，以及对参与 HIV 疫苗临床试验的关注。研究参与者中，35.8%的人非常愿意参与，35.1%的人可能愿意参与，16.4%的人可能不愿意参与，12.7%的人肯定不愿意参与。分析表明，感知到的家庭支持、对 HIV 感染的保护以及担心参与会导致社会疏远与 WTP 相关。中国的 MSM 可能是 HIV 疫苗试验的合适人选。需要进一步研究以评估实际入组情况。
Zotero 插件