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初级保健医生对糖尿病肾病的筛查与治疗

Screening and treatment of diabetic nephropathy by primary care physicians.

作者信息

Kraft S K, Lazaridis E N, Qiu C, Clark C M, Marrero D G

机构信息

Diabetes Research and Training Center, Indiana University School of Medicine, Indianapolis 46202, USA.

出版信息

J Gen Intern Med. 1999 Feb;14(2):88-97. doi: 10.1046/j.1525-1497.1999.00292.x.

Abstract

OBJECTIVE

To describe the practices of Indiana primary care physicians related to diabetic nephropathy screening and management.

DESIGN

Cross-sectional, observational.

SETTING

The state of Indiana.

PARTICIPANTS

Active primary care physicians (defined as general internists, family practitioners, and general practitioners) in Indiana who provided care for diabetic patients at the time of the survey (n = 1,018)

MEASUREMENTS AND MAIN RESULTS

Practice patterns relevant to microalbuminuria and overt albuminuria screening and management were assessed along two dimensions: the percentage of patients to whom the practices were applied and the frequency with which the practices were performed. Of 1,141 physicians who responded to the survey, 1,018 were eligible for analysis. Eighty-six percent of physicians reported screening more than half of their patients with type 1 diabetes for overt albuminuria, as did 82% of physicians for their patients with type 2 diabetes. Only 17% of physicians indicated performing microalbuminuria testing on more than half of their type 1 patients. Angiotensin-converting enzyme inhibitor agents were used frequently to treat abnormal urinary albumin excretion when hypertension was present, but less often when hypertension was absent. Physician specialty, year of graduation from medical school, practice location, and familiarity with the results of the Diabetes Control and Complications Trial were significant predictors of screening and treatment practice patterns.

CONCLUSIONS

Primary care physicians report practices that allow them to detect overt albuminuria but not microalbuminuria. Angiotensin-converting enzyme inhibitors are frequently used by physicians who test for microalbuminuria, but efforts to increase the detection of early renal damage are needed so that these agents and other therapeutic strategies may be employed at the earliest opportunity.

摘要

目的

描述印第安纳州初级保健医生在糖尿病肾病筛查和管理方面的做法。

设计

横断面观察性研究。

地点

印第安纳州。

参与者

印第安纳州积极从事初级保健的医生(定义为普通内科医生、家庭医生和全科医生),在调查时为糖尿病患者提供护理(n = 1018)

测量指标和主要结果

从两个维度评估与微量白蛋白尿和显性白蛋白尿筛查及管理相关的实践模式:应用这些实践的患者百分比以及实践执行的频率。在1141名回复调查的医生中,1018名符合分析条件。86%的医生报告称,他们对超过一半的1型糖尿病患者进行显性白蛋白尿筛查,82%的医生对2型糖尿病患者进行了同样的筛查。只有17%的医生表示对超过一半的1型患者进行微量白蛋白尿检测。当存在高血压时,血管紧张素转换酶抑制剂常用于治疗异常尿白蛋白排泄,但在无高血压时使用较少。医生专业、医学院毕业年份、执业地点以及对糖尿病控制和并发症试验结果的熟悉程度是筛查和治疗实践模式的重要预测因素。

结论

初级保健医生报告的做法能够使他们检测到显性白蛋白尿,但无法检测到微量白蛋白尿。进行微量白蛋白尿检测的医生经常使用血管紧张素转换酶抑制剂,但需要努力提高对早期肾损伤的检测,以便能尽早使用这些药物和其他治疗策略。

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