Wang R, Lu X, Wu M, Wang E
Laboratory of Electroanalytical Chemistry and National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Jilin, PR China.
J Chromatogr B Biomed Sci Appl. 1999 Jan 22;721(2):327-32. doi: 10.1016/s0378-4347(98)00485-x.
Promethazine and thioridazine were separated and detected by capillary electrophoresis with end-column amperometric detection. The influence of pH value on oxidation potential, the peak current and the resolution were studied and the following conditions was selected: 0.03 M Na2HPO4 and 0.015 M citric acid at pH 3.0, detection potential at 1.10 V. The detection limits of these two substances were in the range of 10(-8) mol/l. The linear range spanned two to three orders of magnitude. This method was applied to the detection of promethazine and thioridazine spiked in urine.
采用柱端安培检测的毛细管电泳法对异丙嗪和硫利达嗪进行分离与检测。研究了pH值对氧化电位、峰电流和分离度的影响，并选择了以下条件：0.03 M磷酸氢二钠和0.015 M柠檬酸，pH值为3.0，检测电位为1.10 V。这两种物质的检测限在10(-8) mol/l范围内。线性范围跨越两到三个数量级。该方法应用于尿液中添加的异丙嗪和硫利达嗪的检测。
