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[长效抗精神病药物五氟利多(长哌利定/杨森制药)在精神科治疗中的地位]

[Position of the delayed-action neuroleptic penfluridol (Longperidol/Janssen) in psychiatric therapy].

作者信息

Lange E, König L, Glitschka A, Waldmann K D, Degenhardt T, Niedermeyer K, Zielonka V S, Kühne G E, Schmidt P, Graf K

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1976 Aug;28(8):466-70.

PMID:1005544
Abstract

Longoperidol/Janssen, an orally administered neuroleptic with a five- to seven-day duration of effects, was clinically tested in six mental hospitals in the G.D.R. where the agent was administered to subjects of chronic to subacute schizophrenia. It was not possible for fully consistent results to be obtained in these tests. Workers at mental hospitals in Leipzig and Mühlhausen recommended that the drug should be imported, whereas those at the four other centers (Dresden, Halle, Jena, and Schwerin) did not consider the medication to be indispensable, although they were also able to observe the good effects of the agent.

摘要

长效哌泊噻嗪/杨森公司产品,一种口服抗精神病药物,作用持续时间为五至七天,在民主德国的六家精神病院进行了临床试验,受试对象为慢性至亚急性精神分裂症患者。在这些试验中不可能获得完全一致的结果。莱比锡和米尔豪森精神病院的工作人员建议进口该药物,而其他四个中心(德累斯顿、哈雷、耶拿和什未林)的工作人员虽然也能观察到该药物的良好效果,但并不认为该药物是必不可少的。

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