五氟利多在短期治疗病房新出院精神分裂症患者维持治疗中的应用
Penfluridol in the maintenance treatment of schizophrenic patients newly discharged from a brief therapy unit.
作者信息
Chouinard G, Annable L, Kolivakis T N
出版信息
J Clin Pharmacol. 1977 Feb-Mar;17(2-3):162-7. doi: 10.1002/j.1552-4604.1977.tb04602.x.
Abstract
Penfluridol, a long-acting neuroleptic that can be administered orally once a week, was compared with chlorpromazine in the maintenance treatment of 29 schizophrenic patients newly discharged from a brief therapy unit. The results indicate that penfluridol was of a similar efficacy to chlorpromazine in the treatment of these patients. Penfluridol-treated patients experienced less drowsiness but more extrapyramidal symptoms than those treated with chlorpromazine.
摘要
五氟利多是一种长效抗精神病药物，每周口服一次。在对29名从短期治疗病房新出院的精神分裂症患者进行维持治疗时，将其与氯丙嗪进行了比较。结果表明，在治疗这些患者方面，五氟利多与氯丙嗪疗效相似。与氯丙嗪治疗的患者相比，五氟利多治疗的患者嗜睡症状较少，但锥体外系症状较多。
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