Langberg H, Bülow J, Kjaer M
Department of Rheumatology H, Bispebjerg Hospital, Copenhagen, Denmark.
Clin Physiol. 1999 Jan;19(1):89-93. doi: 10.1046/j.1365-2281.1999.00148.x.
Alteration in tendinous and peritendinous blood flow during and after exercise is suggested to contribute to the development of Achilles tendon injury and inflammation. In the present study a method for evaluating the influence of standardized workload on peritendinous flow is presented. The radioactive isotope xenon-133 was injected just ventrally to the Achilles tendon 5 cm proximal to the tendon's insertion on the calcaneous. The disappearance of 133Xe was used to determine blood flow during intermittent static exercise of the calf muscle (1.5 s exercise/1.5 s rest) for 30 min at a workload equivalent to individual body weight (1 BW) in six healthy volunteers around both Achilles tendons (n = 12). During intermittent static exercise, blood flow was increased from 1.8 +/- 0.3 ml 100 g tissue-1 min-1 (mean value and SEM) (rest) to 6.1 +/- 1.3 ml 100 g tissue-1 min-1 (exercise) (P < 0.05). The exercise induced an average increase in blood flow (3.4-fold) equivalent to results previously obtained during regular dynamic heel raises (P > 0.05). It is concluded that the method is well suited to study the influence of standardized workload on the physiology and pathophysiology of the tissue around the Achilles tendon in humans.
运动期间及运动后腱部和腱周血流的改变被认为与跟腱损伤和炎症的发展有关。在本研究中，提出了一种评估标准化负荷对腱周血流影响的方法。将放射性同位素氙-133注射到跟腱腹侧、距跟腱在跟骨附着点近端5厘米处。利用133Xe的消失来测定6名健康志愿者双侧跟腱周围在相当于个体体重（1BW）的负荷下进行30分钟小腿肌肉间歇性静态运动（1.5秒运动/1.5秒休息）时的血流情况（n = 12）。在间歇性静态运动期间，血流从1.8±0.3毫升100克组织-1分钟-1（平均值和标准误）（休息时）增加到6.1±1.3毫升100克组织-1分钟-1（运动时）（P < 0.05）。该运动引起的血流平均增加（3.4倍）与之前在常规动态足跟抬高时获得的结果相当（P > 0.05）。结论是，该方法非常适合研究标准化负荷对人体跟腱周围组织生理和病理生理的影响。
