White M
Institute of Allergy and Asthma, Washington Hospital Center, Washington, DC 20010, USA.
J Allergy Clin Immunol. 1999 Mar;103(3 Pt 2):S378-81. doi: 10.1016/s0091-6749(99)70215-0.
A complex interplay of inflammatory cells and chemical mediators is responsible for allergic inflammation. It is now understood that the allergic reaction consists of an early-phase response involving mast cell degranulation with the release of histamine and a late-phase response characterized by the migration of inflammatory cells. This review provides a summary of the early- and late-phase events associated with allergic inflammation and an overview of the principal chemical mediators involved in the inflammatory process.
